Results 91 to 100 of about 1,562,553 (261)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The RATF Formula (Kwok's Formula): Exploiting Average Term Frequency in Cross-Language Retrieval
Information Research: An International Electronic Journal, 2002 In an earlier study, we presented a query key goodness scheme, which can be used to separate between good and bad query keys. The scheme is based on the relative average term frequency (RATF) values of query keys.
Ari Pirkola +2 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Using Suffix Arrays to Compute Term Frequency and Document Frequency for All Substrings in a Corpus
Computational Linguistics, 2021 Mikio Yamamoto, Kenneth W. Church
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Drone-Assisted Multimodal Logistics: Trends and Research Issues
DronesThis study explores the evolving trends and research issues in the field of drone-assisted multimodal logistics over the past two decades. By employing various text-mining techniques on related research publications, we identify the most frequently ...
Kyunga Kim +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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A Short-Term Forecasting Method for High-Frequency Broadcast MUF Based on LSTM
AtmosphereThis paper proposes a short-term forecasting method for high-frequency broadcast Maximum Usable Frequency (MUF) based on Long Short-Term Memory (LSTM) to meet the demand for refined and precise high-frequency broadcast coverage.
Shengyun Ji +5 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source