Results 191 to 200 of about 33,047,881 (379)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source
An Immobilization Technique for Long-Term Time-Lapse Imaging of Explanted <i>Drosophila</i> Tissues. [PDF]
Bostock MP+6 more
europepmc +1 more source
Long-Term Real-Time Coastal Ocean Observation Networks [PDF]
Scott Glenn+3 more
openalex +1 more source
Is it time to change the term negative symptoms?
Emilio Fernandez-Egea, Noham Wolpe
openaire +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici+8 more
wiley +1 more source
Modeling long‐term persistence in hydroclimatic time series using a hidden state Markov Model [PDF]
Mark Thyer, George Kuczera
openalex +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf+10 more
wiley +1 more source
Long-term time-series forecasting of social interventions for narcotics use and property crime
Keiko I. Powers+3 more
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu+18 more
wiley +1 more source