Results 231 to 240 of about 12,657,247 (336)

Long Term Outcomes and Durability of Fenestrated Endovascular Aneurysm Repair: A Meta-analysis of Time to Event Data [PDF]

open access: bronze
Aurélien Guéroult   +6 more
openalex   +1 more source

Short-term Time Series Forecasting of Concrete Sewer Pipe Surface Temperature

open access: gold, 2020
Karthick Thiyagarajan   +2 more
openalex   +1 more source

Long Short-Term Memory Neural Networks for Online Disturbance Detection in Satellite Image Time Series [PDF]

open access: gold, 2018
Yunlong Kong   +5 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Short-term time step convergence in a climate model. [PDF]

open access: yesJ Adv Model Earth Syst, 2015
Wan H   +3 more
europepmc   +1 more source

Long-Term Statin Administration Does Not Affect Warfarin Time in Therapeutic Range in Australia or Singapore [PDF]

open access: gold, 2018
Nijole Bernaitis   +6 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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