Results 151 to 160 of about 1,000,237 (275)

Caregiver burden and quality of life in palliative care: cross-sectional study. [PDF]

BMJ Support Palliat Care
Shefeek SK, Joy TM, Olickal JJ, Nezrin MA, George A, Thankappan KR.   +5 more
europepmc   +1 more source

FBP1‐Mediated Compartmentalization of Glycolytic Enzyme Complexes Suppresses PKM2 Function to Ameliorate MASLD Progression

Advanced Science, EarlyView.
In normal hepatocytes, FBP1 forms compartmentalized complexes with PKM2, ENO1, and LDHA independent of its catalytic activity, inhibiting PKM2 activity and restricting excessive glycolysis. During MASLD progression, FBP1 downregulation markedly reduces the abundance of these complexes and releases the “hijacked” glycolytic enzymes, leading to PKM2 ...
Busong Wang, Yiping Tang, Na Li, Xuening Dai, Jing Wu, Bin Xue, Yuxin Chen, Jingzi Zhang, Lingdong Kong, Chaojun Li, Lei Fang   +10 more
wiley   +1 more source

Hydrophobic MFI-Type Zeolites via Alkali-Cation-Induced Defect Healing: Implications for Adsorbent and Catalyst Design. [PDF]

Adv Mater
Kanteler C, Ferri P, Escobar-Bedia FJ, Mayoral Á, Vidal-Moya A, Kendra R, Lei C, Palomino M, Rey F, Grajciar L, Heard CJ, Serna P, Boronat M, Martínez C, Moliner M.   +14 more
europepmc   +1 more source

MODELING QUEUING SYSTEM OF INTERACTION BETWEEN TERMINAL DEVICES AND SERVICES PROVIDERS IN THE BANK

Статистика и экономика, 2016
The article focuses on the development of mathematical models and tools to optimize the system of queuing at the bank. The article discusses the mathematical aspects that will achieve redistribution of transaction flow, reduce the time of the request in the queue, increase the bank’s profit and gain competitive advantage.
openaire   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan, Mengkai Lu, Xinhai Cui, Dawei Zhang, Lei Zhang, Lin Lin, Yuan Li, Yuanlong Hu, Chao Li   +8 more
wiley   +1 more source

A rare case of split cord malformation type II with concomitant myelocystocele: illustrative case. [PDF]

J Neurosurg Case Lessons
Owen BS, Ivey NA, Bierbrauer KS, Nagaraj UD, Patel SK.   +4 more
europepmc   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Fintech-driven sport event sponsorship: how commercial banks' innovative marketing strategies shape destination branding and inclusive tourism. [PDF]

Front Sports Act Living
Atoevna TS, Anvarovich QA, Junaydulloyevich AM, Qizi RDI, Umarovich SA.   +4 more
europepmc   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

Establishment of a novel human nervous system tissue bank: University of Debrecen tissue bank-introduction and retrospective data analysis. [PDF]

Cell Tissue Bank
Bencs V, Hortobágyi T, Nagy AC, Kozák M, Méhes G, Oláh L, Csiba L.   +6 more
europepmc   +1 more source