Results 201 to 210 of about 79,351 (276)

Quantitative Analysis of Locus Coeruleus Neurons and Thalamic Noradrenergic Axons in a Progressive 1‐Methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine Monkey Model of Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson's disease is mainly characterized by dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) and α‐synuclein accumulation. The locus coeruleus (LC) is also affected in Parkinson's disease and linked to some nonmotor symptoms, but the extent and timing of its degeneration remain unclear.
Megan Carrillo   +6 more
wiley   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano   +4 more
wiley   +1 more source

Anti-RGS8 paraneoplastic cerebellar ataxia is preferentially associated with a particular subtype of Hodgkin's lymphoma. [PDF]

open access: yesJ Neurol
Peter E   +22 more
europepmc   +1 more source

Sedum zhenghaianum (Crassulaceae), a new species from Zhejiang and Jiangxi, East China

open access: yesNordic Journal of Botany, EarlyView.
In this paper, Sedum zhenghaianum sp. nov. is described as a new species based on morphological and molecular analyses, and its taxonomic relationships are discussed. Morphological analysis indicates that S. zhenghaianum should be classified in the genus Sedum sect. Sedum and is distinct from the related species S. tosaense in morphology, e.g.
Shi‐Qi She   +6 more
wiley   +1 more source

Prognostic importance of NUP98-rearrangements in acute myeloid leukemia: A systematic review and meta-analysis. [PDF]

open access: yesCaspian J Intern Med
Sheikhi M   +9 more
europepmc   +1 more source

Update on Ouratea cidiana Sastre (Ochnaceae), a microendemic species from the Amazon: enlightening the identity and conservation status

open access: yesNordic Journal of Botany, EarlyView.
Ouratea cidiana (Ochnaceae) is a microendemic shrub species from the Brazilian Amazonia, occurring along the banks of the Trombetas River and restricted to the Cachoeira Porteira region, in western Pará State. Since the original collection nearly forty years ago, no additional records have been made, which is concerning given the continuous decline in ...
Clebiana de Sá Nunes   +4 more
wiley   +1 more source

CAR-T and CAR-NK cell therapies in AML: breaking barriers and charting the future. [PDF]

open access: yesJ Transl Med
Wu H   +8 more
europepmc   +1 more source

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