Results 61 to 70 of about 3,113 (238)

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

The ProCard mobile banking system [PDF]

open access: yesInformatică economică, 2007
The mobile banking involves the use of some mobile telecommunication devices (such phones or PDAs - Personal Digital Assistants) in order to complete, in a secure manner, banking transactions (like payments, transfers, account information and so on).
doaj  

Security internet and terminal banking services in the opinion of cooperative banks customers [PDF]

open access: yesEkonomiczne Problemy Usług, 2017
Anna Nowacka, Mariola Szewczyk-Jarocka
openaire   +1 more source

Navigating Reputational Risks: Cautionary Considerations for South African Banks in the Unilateral Termination of Bank-Customer Relationships

open access: yesPotchefstroom Electronic Law Journal
Bredenkamp v Standard Bank of South Africa Ltd (SCA) and subsequent cases that followed this precedent exhibit that banks have the right to terminate the bank-customer relationship unilaterally. This right is usually entrenched in the contract between the bank and its customer and may also have its origin in an implied term of the contract.
openaire   +3 more sources

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu   +10 more
wiley   +1 more source

FROM BANKS TO BANKING - A NEW ERA OF CUSTOMER FOCUSED INNOVATION

open access: yesМир новой экономики, 2018
Today internet banking can be called one of the most perspective ways of granting financial retail products. The innovative solutions proposed by nowdays created financial companies make essential impact on shift of customer priorities and expactations ...
TATYANA Konevtseva
doaj  

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

open access: yesAdvanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang   +15 more
wiley   +1 more source

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

open access: yesAdvanced Science, EarlyView.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo   +14 more
wiley   +1 more source

Applications of Parallel Processing in Mobile Banking [PDF]

open access: yesInformatică economică, 2007
The future of mobile banking will be represented by such applications that support mobile, Internet banking and EFT (Electronic Funds Transfer) transactions in a single user interface. In such a way, the mobile banking will be able to cover all the types
doaj  

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

open access: yesAdvanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui   +9 more
wiley   +1 more source

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