Results 141 to 150 of about 1,000,117 (351)

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Mobility Management in beyond 3G-Environments [PDF]

open access: yes, 2003
Beyond 3G-environments are typically defined as environments that integrate different wireless and fixed access network technologies. In this paper, we address IP based Mobility Management (MM) in beyond 3G-environments with a focus on wireless access ...
Bargh, Mortaza S.   +4 more
core   +1 more source

Developing palliative and end-of-life care research partnerships in the North East and North Cumbria: A report on the first year of the RIPEN network

open access: yesHealth and Social Care Delivery Research
Background The North East is one of the most disadvantaged areas of England with end-of-life care needs shaped by high levels of disability, physical and mental ill health.
Katherine Frew   +14 more
doaj   +1 more source

Physician-assisted suicide in Italy: where do we stand and where do we want to go?

open access: yesFrontiers in Psychiatry
Physician-assisted suicide (PAS) remains a subject of global debate and ethical controversy, alongside other end-of-life issues such as euthanasia, palliative care, access to health and social care services, and, importantly, patient autonomy.
Emanuela Turillazzi   +3 more
doaj   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

RRP9 Promotes Esophageal Squamous Cell Carcinoma Progression through E2F1 Transcriptional Regulation of CDK1

open access: yesAdvanced Biology, EarlyView.
The study reveals that RRP9 is abnormally highly expressed in ESCC tissues and is closely associated with poor prognosis in patients. Furthermore, it is found that RRP9 promotes ESCC progression through enhancing the E2F1‐mediated transcriptional regulation of CDK1.
Gang He   +14 more
wiley   +1 more source

Analyzing the determinants of willingness-to-pay values for testing the validity of the contingent valuation method. Application to home care compared to hospital care [PDF]

open access: yes
The contingent valuation (CV) method is an attractive approach for comparing home care to hospital care in which the only difference is patients' well-being during the treatment process and not health outcomes.
Magali Morelle   +3 more
core  

Solutions for IPv6-based mobility in the EU project MobyDick [PDF]

open access: yes, 2002
Proceedings of the WTC 2002, 18th World Telecommunications Congress, Paris, France, 22 -27 September, 2002.Mobile Internet technology is moving towards a packet-based or, more precisely, IPv6-based network.
Jähnert, Jürgen   +7 more
core   +2 more sources

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