Results 61 to 70 of about 500,409 (312)

Terminal Guidance Law for UAV Based on Receding Horizon Control Strategy

Complexity, 2017
Terminal guidance law against the maneuvering target is always the focal point. Most of the literatures focus on estimating the acceleration of target and time to go in guidance law, which are difficult to acquire. This paper presents a terminal guidance
Zhenglong Wu, Zhenyu Guan, Chengwei Yang, Jie Li   +3 more
doaj   +1 more source

Analysis of the Influence of Trace Point Step-Jump Behavior

International Journal of Aerospace Engineering, 2020
To explore the influence of the trace point step-jump behavior on a terminal guidance system, an analysis is performed from the line-of-sight rate (LOS rate) and guidance accuracy views for designing an anti-step-jump guidance law.
Yao Yang, Yang Xu, Pei Wang
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Optimal on-off cooperative manoeuvers for long-term satellite cluster flight [PDF]

, 2014
When a group of satellites is equipped with a particulary simple propul- sion system, e.g. cold-gas thrusters, constraints on the thrust level and total propellant mass renders cluster-keeping extremely challenging.
Gurfil, Pini, Mazal, Leonel, Mingotti, Giorgio   +2 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Adaptive Fuzzy Sliding Mode Guidance Law considering Available Acceleration and Autopilot Dynamics

International Journal of Aerospace Engineering, 2018
Terminal guidance law for missiles intercepting high maneuvering targets considering the limited available acceleration and autopilot dynamics of interceptor is investigated.
Yulin Wang, Shengjing Tang, Wei Shang, Jie Guo   +3 more
doaj   +1 more source

The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance [PDF]

, 2011
The multiprotein complexes that receive and transmit axon pathfinding cues during development are essential to circuit generation. Here, we identify and characterize the Drosophila sterile α-motif (SAM) domain-containing protein Caskin, which shares ...
Broihier, Heather T, DiAntonio, Aaron, Liu, Nan, Weng, Yi-Lan   +3 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Terminal Guidance with Attack Time and Impact Angle Constraints for Hypersonic Vehicle in Dive Phase

International Journal of Aerospace Engineering, 2018
The terminal guidance problem of hypersonic gliding missiles under multiple constraints was considered regarding a coordinated attack in time and space.
Zhao-ting Li, Hong-bo Zhang
doaj   +1 more source