Results 241 to 250 of about 807,861 (314)

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Physician Assisted Suicide [PDF]

, 1995
Miech, Ralph P.
core   +1 more source

IgG4-related disease masquerading as malignancy in the abdomen: A diagnostic challenge. [PDF]

Radiol Case Rep
Rahmatullah ZF, Hruban RH, Fishman EK.
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Obturator Foramen Bypass With Fluoroscopic Guidance for Recurrent Femoral Prosthetic Bypass Occlusions: A Case Report. [PDF]

Cureus
Yasumura H, Arata K, Imada R, Satozono H, Shimoishi K, Fukumoto Y, Yotsumoto G, Ogata Y, Matsuba T, Soga Y.   +9 more
europepmc   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Improvement in small-bowel and colonic lesions observed by intestinal ultrasonography in Crohn's disease treated with risankizumab. [PDF]

Medicine (Baltimore)
Miyakawa M, Nasuno M, Nojima M, Konno A, Shimoyama K, Hamada T, Sugiyama K, Tanaka H.   +7 more
europepmc   +1 more source

Euthanasia and Natural Law [PDF]

, 1978
Colbert, James G.
core   +1 more source

Exploring targeted therapy in retinal vasculopathy with cerebral leukoencephalopathy: a case report and review of literature. [PDF]

Front Immunol
Tato-Moreno P, Lavilla Olleros C, Balastegui Martín H, Barrientos Guerrero M, Mensa-Vilaro A, Durán-García ME, Sánchez-Mateos P, García-Martínez E.   +7 more
europepmc   +1 more source

Peroneal Artery "Terminal" Perforator Pedicled Flap for Surrounding Soft Tissue Defects: A Retrospective Cohort Study. [PDF]

Orthop Res Rev
Lu Y, Jin P, Wang B, Gu J, Liu H.
europepmc   +1 more source