Results 41 to 50 of about 30,129 (214)

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman   +10 more
wiley   +1 more source

External validation of multimodal termination of resuscitation rules for out-of-hospital cardiac arrest patients in the COVID-19 era

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2021
Background Futile resuscitation for out-of-hospital cardiac arrest (OHCA) patients in the coronavirus disease (COVID)-19 era can lead to risk of disease transmission and unnecessary transport.
Haewon Jung   +12 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Employment Termination from the Point of View of Good Morals [PDF]

open access: yesSocietas et Iurisprudentia, 2015
The present paper deals with the issue of invalidity of employment termination, where the employment is terminated on the basis of a legal act, and where the non-compliance with good morals applies.
Andrea Olšovská, Miriam Laclavíková
doaj  

Termination of Graph Transformation Systems Using Weighted Subgraph Counting [PDF]

open access: yesLogical Methods in Computer Science
We introduce a termination method for the algebraic graph transformation framework PBPO+, in which we weigh objects by summing a class of weighted morphisms targeting them. The method is well-defined in rm-adhesive quasitoposes (which include toposes and
Roy Overbeek, Jörg Endrullis
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

A Jurisprudential and Legal Study of the Effect of Termination Compared to Previous Contracts [PDF]

open access: yesآموزه‌‌های فقه مدني, 2020
Traditionally, one of the distinguishing features of termination and annulment of a contract is considered to be that annulment makes the contract ineffective from the beginning, and termination has no effect on the past and makes the contract ...
Mahdi Chegeni   +1 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Consistency and Completeness of Rewriting in the Calculus of Constructions [PDF]

open access: yesLogical Methods in Computer Science, 2008
Adding rewriting to a proof assistant based on the Curry-Howard isomorphism, such as Coq, may greatly improve usability of the tool. Unfortunately adding an arbitrary set of rewrite rules may render the underlying formal system undecidable and ...
Daria Walukiewicz-Chrzaszcz   +1 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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