Results 51 to 60 of about 984,200 (299)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Користувацька угода (Terms of Servise, ToS) в координатах «епохи наглядового капіталізму»

Аналітично-порівняльне правознавство
Стаття присвячена дослідженню правової природи користувацьких угод на тлі сучасного соціокультурного контексту. За основу аналізу поточного соціокультурного моменту взято працю Ш. Зубофф «Епоха наглядового капіталізму».
V. M. Vovk
doaj   +1 more source

Examining the Service Quality of Private Gym Customers in terms of Some Demographic Variables

Sportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2020
In this study, it was aimed to examine the quality of service expected and perceived by the customers of private gyms in terms of some demographic variables. The research was designed in the survey model, which is one of the quantitative research methods.
Melike Esentaş, Kadir Yıldız, Pınar Güzel   +2 more
doaj   +1 more source

An Investigation of Pre-Service Classroom Teachers’ Science Process Skills in Terms of Some Variables

Kuramsal Eğitimbilim Dergisi, 2013
The purpose of this study is to determine levels of science process skills of pre-service classroom teachers and to examine relationships between their science process skills and science achievement. The study had a descriptive survey design.
Bülent AYDOĞDU, Serkan BULDUR
doaj   +1 more source

Rethinking 'Terms of Service' through programmatic time travel

The contexts of design are constantly changing, sometimes to the extent that once a ‘good’ designerly response to an issue, over time becomes increasingly problematic. Therefore, there is often a need to rethink design and its concepts.
Özçetin, Seda,, Redström, Johan,, Redström, Johan, Özçetin, Seda   +3 more
core   +1 more source

New Aspects of Research into Service Encounters and Service Quality

, 2006
Purpose: The objective is two-fold. The first is to describe contemporary and future penetration (i.e. analysis and understanding) in service encounter research.
Svensson, Göran,
core   +1 more source

Ontology-based composition and matching for dynamic service coordination [PDF]

, 2011
Service engineering needs to address integration problems allowing services to collaborate and coordinate. The need to address dynamic automated changes - caused by on-demand environments and changing requirements - can be addressed through service ...
Yapa Bandara, Kosala, Kosala Yapa Bandara, Wang, MingXue, Claus Pahl, Pahl, Claus, Veronica Gacitua-decar, Gacitua-Decar, Veronica, Mingxue Wang, Kosala Yapa   +8 more
core   +1 more source

From quality control to TQM, service quality and service sciences : a 30-year review of TQM literature

, 2022
Purpose: This paper aims to review total quality management (TQM) literature in the past three decades to identify the quality related key terms, to analyse their linkage among the identified key terms and their developmental trends.
Dahlgaard, Jens Jörn,, Dahlgaard-Park, Su Mi,, Chen, Chi Kuang,, Chen, Chi-Kuang,, Reyes, Lidia,, Dahlgaard, Jens,, Dahlgaard, Jens, Chen, Chi-Kuang, Reyes, Lidia, Chen, Chi Kuang, Dahlgaard-Park, Su Mi, Lund University., Dahlgaard, Jens Jörn   +12 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source