Results 111 to 120 of about 2,344 (236)

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Integrating Life-Cycle Assessment (LCA) and Artificial Neural Networks (ANNs) for Optimizing the Inclusion of Supplementary Cementitious Materials (SCMs) in Eco-Friendly Cementitious Composites: A Literature Review. [PDF]

Materials (Basel)
Arvizu-Montes A, Guerrero-Bustamante O, Polo-Mendoza R, Martinez-Echevarria MJ.   +3 more
europepmc   +1 more source

Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA. [PDF]

Nucleic Acids Res, 2023
Lou YC, Huang HY, Yeh HH, Chiang WH, Chen C, Wu KP.   +5 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Inpainting of damaged temple murals using edge- and line-guided diffusion patch GAN. [PDF]

Front Artif Intell
Sumathi G, Uma Devi M.
europepmc   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Cognitive constraints and lexicogrammatical variability in ASD: from diagnostic discriminators to intervention strategies. [PDF]

Front Hum Neurosci
Kato S, Hanawa K.
europepmc   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Interface-aware molecular generative framework for protein-protein interaction modulators. [PDF]

J Cheminform
Wang J, Mao J, Li C, Xiang H, Wang X, Wang S, Wang Z, Chen Y, Li Y, No KT, Song T, Zeng X.   +11 more
europepmc   +1 more source

On the Order of the Discriminant of a Ternary Form. [PDF]

Proceedings of the London Mathematical Society
openaire   +1 more source