Results 131 to 140 of about 2,344 (236)

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid. [PDF]

Nat Microbiol
McLean TC, Balaguer-Pérez F, Chandanani J, Thomas CM, Aicart-Ramos C, Burick S, Olinares PDB, Gobbato G, Mundy JEA, Chait BT, Lawson DM, Darst SA, Campbell EA, Moreno-Herrero F, Le TBK.   +14 more
europepmc   +1 more source

Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants

Advanced Healthcare Materials, EarlyView.
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay, Bryson White, Susmita Bose, Amit Bandyopadhyay   +3 more
wiley   +1 more source

Crystal Composition Transformer: Self-Learning Neural Language Model for Generative and Tinkering Design of Materials. [PDF]

Adv Sci (Weinh)
Wei L, Li Q, Song Y, Stefanov S, Dong R, Fu N, Siriwardane EMD, Chen F, Hu J.   +8 more
europepmc   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

Cross-subject EEG signals-based emotion recognition using contrastive learning. [PDF]

Sci Rep
Alghamdi AM, Ashraf MU, Bahaddad AA, Almarhabi KA, Al Shehri WA, Daraz A.   +5 more
europepmc   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

In situ evidence for serpentinization within the Máaz formation, Jezero crater, Mars. [PDF]

Sci Adv
Tosca NJ, Tice MM, Hurowitz JA, Pedersen DAK, Henneke J, Mandon L, McCubbin FM, Ross O, Tung PY, Harrison RJ, Li A, Schmidt ME, Kizovski TV, Liu Y, Mayhew L, Jones MWM, Labrie J, Davidoff S, Allwood AC, Beyssac O, Brown A, Cable M, Comellas J, Clark BC, Galvin AE, Horgan B, Heirwegh CM, Nemere P, Orenstein BJ, Quantin-Nataf C, Royer C, Treiman A, Wade LA, Wiens R, Wright AP.   +34 more
europepmc   +1 more source

Biofabrication of Endothelialized, Intrinsically Vascularized 3D‐Printed Recombinant Spider Silk Scaffolds

Advanced Healthcare Materials, EarlyView.
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold, Stefanie Heltmann‐Meyer, Xuen J. Ng, Thomas Scheibel, Tobias Fey, Harald Wajant, Carol Geppert, Andreas Arkudas, Dominik Steiner, Raymund E. Horch   +9 more
wiley   +1 more source

Precise Size Determination of Supported Catalyst Nanoparticles via Generative AI and Scanning Transmission Electron Microscopy. [PDF]

Small Methods
Eliasson H, Lothian A, Surin I, Mitchell S, Pérez-Ramírez J, Erni R.   +5 more
europepmc   +1 more source