Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation. [PDF]
Abstract Background and Purpose Guanylyl cyclase‐A (GC‐A), activated by endogenous atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), plays an important role in the regulation of cardiovascular and renal homeostasis and is an attractive drug target. Even though small molecule modulators allow oral administration and longer half‐life,
Andresen H +8 more
europepmc +2 more sources
Diagnostic accuracy of sliding sign for detecting pouch of Douglas obliteration and bowel involvement in women with suspected endometriosis: systematic review and meta-analysis. [PDF]
ABSTRACT Objective The aim of this systematic review and meta‐analysis was to evaluate the diagnostic accuracy of the sliding sign on transvaginal ultrasound (TVS) in detecting pouch of Douglas obliteration and bowel involvement in patients with suspected endometriosis, using laparoscopy as the reference standard.
Alcázar JL +6 more
europepmc +2 more sources
Direct Observation of Liquid–Solid Two‐Phase Seed Particle‐Assisted Kinking in GaP Nanowire Growth
The Cu‐assisted gallium phosphide (GaP) nanocrystal growth is directly observed by supplying metal–organic precursors to Cu nanoparticles inside a transmission electron microscope. The accumulation of Ga atoms in the Cu‐based seed particles by controlled precursor supply variations creates liquid–solid two‐phase seed particles.
Tianyi Hu +7 more
wiley +1 more source
Refining the Lorenz‐ranking of rules for claims problems on restricted domains
Abstract The comparison of the central rules for claims problems, according to the Lorenz order, has been studied not only on the entire set of problems but also on some restricted domains. We provide new characterizations of the adjusted proportional rule as being Lorenz‐maximal or Lorenz‐minimal within a class of rules on the half‐domains. Using this
Miguel Ángel Mirás Calvo +3 more
wiley +1 more source
Aristotle vs. Plato: The classical origins of capitalist & socialist political economies*
Abstract Competing definitions of justice in Plato's Republic and Aristotle's Politics indicate the existence of two distinct economic systems with different priorities. The three‐class society of the Platonic economy (guardians, auxiliaries, producers) gives rise to guardians who by virtue are expected to enforce output targets on producers directly ...
Theocharis Grigoriadis
wiley +1 more source
Background: There is increasing evidence of cross‐reactivity between allergens of close or distant species. The A‐RISC (Allergens'–Relative Identity, Similarity and Cross‐reactivity) index helps evaluate the risk of theoretical cross‐reactivity between proteins of the same family among different species.
Thierry Olivry +2 more
wiley +1 more source
Influence of the Total Porosity on the Properties of Sintered Materials—A Review
Porosity is a characteristic present in most sintered materials, full densification only being achieved in special cases. For some sintered materials, porosity is indeed a desired characteristic, serving for the intended application of the material.
F. Ternero +4 more
semanticscholar +1 more source
The EPICTER score: a bedside and easy tool to predict mortality at 6 months in acute heart failure
Abstract Aims Estimating the prognosis in heart failure (HF) is important to decide when to refer to palliative care (PC). Our objective was to develop a tool to identify the probability of death within 6 months in patients admitted with acute HF. Methods and results A total of 2848 patients admitted with HF in 74 Spanish hospitals were prospectively ...
Miriam Romero‐Correa +143 more
wiley +1 more source
Identificación de Bacillus toyonensis en heces de ganado cebú en el Departamento de Sucre, Colombia
Se evaluaron las características probióticas de cepas nativas aisladas de ganado cebú y se realizó identificación molecular de una de estas cepas, para considerar su posterior aplicación como aditivos microbianos en la alimentación bovina.
Lina Marcela Bertel Mesa +2 more
doaj +1 more source
Background and Purpose cGMP underpins the bioactivity of NO and natriuretic peptides and is key to cardiovascular homeostasis. cGMP‐driven responses are terminated primarily by PDEs, but cellular efflux via multidrug resistance proteins (MRPs) might contribute.
Robert M. H. Grange +9 more
wiley +1 more source

