Results 11 to 20 of about 150,690 (307)
Anatomy of a Stablecoin's failure: the Terra-Luna case [PDF]
Finance Research Letters, 2022 We quantitatively describe the main events that led to the Terra project's failure in May 2022. We first review, in a systematic way, news from heterogeneous social media sources; we discuss the fragility of the Terra project and its vicious dependence ...
Antonio Briola +3 more
semanticscholar +1 more source
bioRxiv, 2023 Telomerase-negative tumors maintain telomere length by alternative lengthening of telomeres (ALT), but the underlying mechanism behind ALT remains poorly understood.
Roshan Vaid +16 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Over the past decade, studies have shown that eukaryotic telomeres are transcribed producing a G-rich RNA termed TERRA. It has been assumed that this RNA is purely structural and does not encode proteins.
Taghreed M. Al-Turki, J. Griffith
semanticscholar +1 more source
Telomere-specific regulation of TERRA and its impact on telomere stability.
Seminars in Cell and Developmental Biology, 2023 TERRA is a class of telomeric repeat-containing RNAs that are expressed from telomeres in multiple organisms. TERRA transcripts play key roles in telomere maintenance and their physiological levels are essential to maintain the integrity of telomeric DNA.
Julieta Rivosecchi +2 more
semanticscholar +1 more source
Nucleic Acids Research, 2023 Telomeres are the nucleoprotein structures at the ends of linear chromosomes. Telomeres are transcribed into long non-coding Telomeric Repeat-Containing RNA (TERRA), whose functions rely on its ability to associate with telomeric chromatin. The conserved
R. Fernandes, J. Lingner
semanticscholar +1 more source
TERRA stability is regulated by RALY and polyadenylation in a telomere-specific manner.
Cell Reports, 2023 Telomeric repeat-containing RNA (TERRA) is a long non-coding RNA transcribed from telomeres that plays key roles in telomere maintenance. A fraction of TERRA is polyadenylated, and the presence of the poly(A) tail influences TERRA localization and ...
Valeria Savoca +9 more
semanticscholar +1 more source
Earth and Planetary Science Letters, 2020 We present a systematic, metre-scale characterisation of the 3D morphometry of an esker on Mars, and the first attempt to reconstruct the multi-stage dynamics of esker formation on Mars.
F. Butcher +7 more
semanticscholar +1 more source
Workplace Health & Safety, 2022 Background: Many workers shifted to working from home due to the COVID-19 pandemic. This review aims to investigate if this sudden change caused an increase in TElewoRk-RelAted stress (TERRA) which is defined as physical and mental stress caused by ...
M. Gualano +6 more
semanticscholar +1 more source
Nature Communications, 2021 Alternative Lengthening of Telomeres (ALT) is a Break-Induced Replication (BIR)-based mechanism elongating telomeres in a subset of human cancer cells. While the notion that spontaneous DNA damage at telomeres is required to initiate ALT, the molecular ...
Bruno Silva +3 more
semanticscholar +1 more source
TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity
Scientific Reports, 2021 Telomere dysfunction causes chromosomal instability which is associated with many cancers and age-related diseases. The non-coding telomeric repeat-containing RNA (TERRA) forms a structural and regulatory component of the telomere that is implicated in ...
Y. Mei +7 more
semanticscholar +1 more source