Results 101 to 110 of about 117,647 (222)

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

open access: yesAdvanced Science, EarlyView.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo   +8 more
wiley   +1 more source

Interfacial Synergy in a Band‐Aligned Low‐Dimensional Heterojunction Toward Broadband Photodetection

open access: yesAdvanced Science, EarlyView.
Monolithically integrating sensing and communication, a Ta2NiSe5/Sb2Te3 heterojunction achieves visible‐to‐near‐infrared photovoltaics with high‐speed terahertz photo‐thermoelectric detection at room temperature. By engineering a Type‐II van der Waals heterojunction, we overcome the intrinsic spectral limitations and disparate physical requirements of ...
Yuanfeng Wen   +20 more
wiley   +1 more source

Oxide Growth and Place-Exchange on Au(111) in Alkaline Electrolyte. [PDF]

open access: yesACS Electrochem
Moser T   +3 more
europepmc   +1 more source

Spectroscopic Evidence of Edge‐Localized States in an Antiferromagnet Topological Insulator NdBi

open access: yesAdvanced Science, EarlyView.
Using spin‐polarized scanning tunneling microscopy (STM) in conjunction with quasiparticle interference, we successfully identify distinct signatures of the ferromagnetic and antiferromagnetic terminations in NdBi, a rare‐earth monopnictide exhibiting non‐trivial topology and magnetism. We demonstrate that step edges on ferromagnetic surfaces host well‐
Avior Almoalem   +8 more
wiley   +1 more source

Terraced fields increased soil organic carbon content in croplands of the loess plateau. [PDF]

open access: yesSci Rep
Wang Q   +12 more
europepmc   +1 more source

AI‐Assisted Self‐Powered Wearable Dual‐Mode Sensor With TENG and Stretchable Optical Fiber for Neurological Disorder Diagnostics

open access: yesAdvanced Science, EarlyView.
This manuscript presents the WDMS platform, an AI‐assisted, self‐powered wearable dual‐mode sensor for tele‐neurology. It integrates a contact–separation TENG insole with stretchable polyurethane optical‐fiber strain sensors to synchronously track plantar pressure and lower‐limb muscle deformation.
Tianliang Li   +12 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy