Results 81 to 90 of about 1,116,264 (246)
Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target
Advanced Science, EarlyView.Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen +12 more
wiley +1 more source
Groningen Journal of International LawIn this article, I present a proposal for an international law-based formula to mediate territorial conflicts, and apply it to the separatist cases in Georgia. While the situation there is notably more stable than in some other post-Soviet conflicts (i.e.
Tero Lundstedt
doaj +1 more source
MEMBANGUN DAN MENGELOLA KAWASAN PERBATASAN: MENJAGA KEUTUHAN DAN MEMPERTAHANKAN KEDAULATAN INDONESIA
Masalah-Masalah Hukum, 2015 Indonesia should be able to maintain its territorial integrity and its sovereignty, including parts of Indonesia border. The problem is not just to set of and affirmed the border line but how to put the border region as part of Indonesian territory ...
Tundjung Herning Sitabuana
doaj +1 more source
Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy
Advanced Science, EarlyView.A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu +15 more
wiley +1 more source
Waterways, hydraulic powers and territorial integrity of Hungary /
, 1919 Pamphlet.Mode of access ...
Viczián, Edward.
core
Advanced Science, EarlyView.This study systematically assessed the global burden and temporal trends of EOTBL cancer in individuals aged 15–49 years. Smoking, ambient particulate matter pollution, and secondhand smoke remain dominant risk factors. Countries within the same Human Development Index (HDI) category exhibit distinct epidemiological trajectories, underscoring the need ...
Ye Tian +8 more
wiley +1 more source
Polarization Holographic 4D Phenotyping Reveals Nanoplastic Induced Dysfunction in Zooplankton
Advanced Science, EarlyView.Contaminant‐induced dysfunction in complex aquatic organisms remains difficult to resolve across scales. Polarization Holographic Imaging Microscopy (PHIM) integrates polarization‐sensitive holography with computational volumetric reconstruction for label‐free phenotyping of zooplankton in natural seawater, revealing that nanoplastic stress drives ...
Yuxing Li +8 more
wiley +1 more source
Baltic Journal of European studies, 2019 The article is devoted to the experience of the application of a concept of militant democracy in modern Ukraine. This concept is relevant due to the prolonged domination of the communist totalitarian regime until 1991, and also in view of the ...
Barabash Yurii, Berchenko Hryhorii
doaj +1 more source
, 2012 The surface integrity plays a very important rule in this functional performance, being dependent of a large number of machining parameters. The major concern of the industry is to know which combination of machining parameters provides a better surface ...
OUTEIRO, José +1 more
core
Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues
Advanced Science, EarlyView.Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali +2 more
wiley +1 more source