Results 51 to 60 of about 1,702,895 (242)

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Closing the Loop: High‐Precision 3D Photofabrication in Living Tissues

Advanced Science, EarlyView.
Writing 3D microstructures inside living tissue demands more than laser access; It demands information. Hierarchical sensing captures thermal and mechanical states across pulse‐train, voxel, and structure timescales, feeding a controller that steers the laser in real time.
Amirbahador Zeynali, Mangirdas Malinauskas, Giuseppe Chirico   +2 more
wiley   +1 more source

Territorial intelligence and inclusive growth: towards an inclusive territorial intelligence system in Salé city

International Journal of Accounting, Finance, Auditing, Management and Economics, 2022
Cet article donne un aperçu sur l’étude empirique relative au développement durable des villes intelligentes à travers une croissance inclusive. La littérature relative à cette étude est axée sur l’ensemble des actions de la ville intelligente, surtout l’intégration des « composants » de la transformation urbaine comme réponse aux enjeux de la ville ...
IKHMIM, Siham, ELMOUADDINE, Hanan, ALIJ, Noureddine   +2 more
openaire   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Commoning of territorial heritage and tools of participated sustainability for the production and enhancement of agro-environmental public goods

Agricultural and Food Economics, 2021
The purpose of this paper is to analyze how the commoning heritage processes find application for the production of agro-environmental public goods in contexts of high socio-economic marginality and environmental vulnerability, characterized by ...
G. Fabiola Safonte, Claudio Bellia, Pietro Columba   +2 more
doaj   +1 more source

The Geography of Success: A Spatial Analysis of Export Intensity in the Italian Wine Industry

Agribusiness, EarlyView.
ABSTRACT This paper investigates the paradox of how Italy's fragmented, SME‐dominated wine industry achieves global export success. Moving beyond purely firm‐centric explanations, we test whether export intensity is spatially dependent, clustering geographically in regional ecosystems.
Nicolas Depetris Chauvin, Jonas Di Vita
wiley   +1 more source

BesançonDijon2013 12e INTI Conference «Territorial Intelligence, Socio-Ecological Transition and Resilience of the Territories »

, 2013
International Conference of Territorial Intelligence "Territorial Intelligence, Socio-Ecological Transition and Resilience of the Territories" 30-31 May 2013, Besançon (UFR SLHS, MSHE), Dijon (MSHD) Since the First Oil Shock, crises have compelled us ...
INTI
core   +1 more source

The fractal or scaling perspective on progressively generated intra-urban clusters from street junctions

International Journal of Digital Earth, 2023
The underlying complexity of urban space can be manifested by its fractal forms and scaling statistics. This paper examines these characteristics at the intra-urban scale through the lens of clustered street junctions (including road ends) in two Chinese
Biao He, Renzhong Guo, Minmin Li, Ying Jing, Zhigang Zhao, Wei Zhu, Chen Zhang, Chengyue Zhang, Ding Ma   +8 more
doaj   +1 more source

Competitive Intelligence For Insular Territories

, 2020
For centuries, the intrinsic and ubiquitous parameters of insular territories have governed social, economic and political life within the island and with outer territories. Besides some biological and physical determinism, there exists a psychological factor that conducts islanders to feel that they possess a rich and a unique identity (Gombaud, 2007 ...
Fournie, Pierre, Dou, Henri
openaire   +4 more sources

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source