Results 61 to 70 of about 1,020,554 (347)
A Generative Neuro‐Symbolic AI for Protein Sequence Design
Advanced Science, EarlyView.We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne +12 more
wiley +1 more source
ILLEGAL FISHING IN INDONESIA FROM THE NATIONAL AND THE INTERNATIONAL LAW PERSPECTIVE
Jurnal Hukum Internasional, 2013 Indonesia is the world’s largest maritime country, its maritime resources need to be guarded and managed continuously for the welfare and prosperity of the people of Indonesia.
Mutiara Hikmah
doaj +1 more source
Advanced Science, EarlyView.Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu +16 more
wiley +1 more source
Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
Advanced Science, EarlyView.How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source
Maritime Boundary Arrangements with Other Countries and The Economic Impact on Indonesian Fishermen [PDF]
BIO Web of ConferencesIndonesia is greatly interested in maritime borders with other countries as a maritime country. This is because it influences the country’s security and citizens’ socio-economy. As is known, the number of fishermen in Indonesia is vast, around 1,500. 000
Suryadi Suryadi +3 more
doaj +1 more source
Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy
Advanced Science, EarlyView.A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu +15 more
wiley +1 more source
Discurso que en la solemne apertura de la Audiencia Territorial el 2 de enero de 1844 [PDF]
Contiene además con port. propia: Manifiesto del número de causas y expedientes criminales y civiles despachados en la Audiencia Territorial de Oviedo en el año ...
Álvarez Celleruelo, Pedro +1 more
core
Advanced Science, EarlyView.Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang +9 more
wiley +1 more source
A multidisciplinary approach to the spatial dimension in ecosystem-based fisheries management
Aquatic Living Resources, 2018 This study considers how to reconcile different spatial scales to find the best common denominator to be used as an ecosystem-based management unit. For this, two fishery production zones differing ecologically, economically, legally and institutionally ...
Le Floc'h Pascal +5 more
doaj +1 more source
Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice
Advanced Science, EarlyView.CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu +8 more
wiley +1 more source