Results 41 to 50 of about 147,172 (267)

L’expérience du conseil de développement de la communauté urbaine de Nantes dans la construction d’une démocratie participative locale

open access: yesL'Espace Politique, 2010
The author examines the influence of various structures born from the civic community in the urban centrer of Nantes on public policies: Institut Kervégan since 1977, consultative conferences since 1996; Development council, journal "Place publique ...
Jean Renard
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Importance of transport security in the realization of Russia’s national interests

open access: yesПутеводитель предпринимателя, 2020
Only the presence and intensive development of the transport infrastructure in the Russian Federation, including all existing modes of transport, including road, rail, air, inland water, sea, other modes of transport, can ensure the sustainable ...
A. M. Novozhilov
doaj  

Modos de vida, territórios e uma cidade em questão: resistências políticas de comunidades rurais no município de São Luís – Maranhão, Brasil

open access: yesL'Ordinaire des Amériques, 2016
This articles studies the political activism of the rural communities of the village of São Luís, in the Brazilian state of Maranhão. Their collective actions are described through the different ways they have found to reclaim their territories and ...
Elio de Jesus Pantoja Alves
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Nationalism, territoriality and national territorial belonging

open access: yesPapers. Revista de Sociologia, 2010
La mayoría de los estudios sobre el nacionalismo entiende la nación como una colectividad cultural que se puede situar en términos históricos en la transición de la época premoderna a la moderna. Se ha prestado menos atención a consideraciones de espacio. En este contexto, este artículo propone que no podemos comprender totalmente tanto el nacionalismo
openaire   +6 more sources

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