Results 131 to 140 of about 1,080,011 (366)
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Kerala Journal of PsychiatryBackground: Treatment with mirtazapine is reported to cause weight gain and adverse metabolic profile in several populations. Limited information is available regarding the metabolic adverse effects of mirtazapine in the Indian population.
Salma Nazim, S Asha, Mili Babu
doaj +1 more source
Port Elizabeth’s tertiary care reaches crisis point
South African Medical Journal, 2012 Almost across disciplines, health care in the Port Elizabeth Provincial Hospital Complex (PEPHC) has deteriorated so badly in the past six months that short-staffed departmental heads are unapologetically cutting back on vital patient services to focus only on the very sick and dying.
openaire +3 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
2015 Physicians Licensure Survey Instrument [PDF]
, 2019 In 2015 all Indiana Physicians who biennially renewed their license electronically were invited to complete this voluntary Survey Instrument administered by the Indiana Professional Licensing Agency (IPLA).
Maxey, Hannah, Randolph, Courtney
core
Association of Genital Chlamydia trachomatis Infection with Female Infer-tility, Study in a Tertiary Care Hospital in Eastern India [PDF]
, 2015 Mallika Ghosh +4 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Assessment of asthma control using the asthma control test at a tertiary care centre in Karachi, Pakistan [PDF]
, 2009 The aim of our study was to assess asthma control among asthmatics at a tertiary care setting in Karachi using ACT questionnaire. The ACT questionnaire was filled by known asthmatics in January 2007. A total of 150 questionnaires were filled of which, 61
Gowani, Saqib Ali +3 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Assessment of Oral Health Promotion Programs in Schools and their Long-Term Effects
Journal of Pharmacy and Bioallied SciencesBackground: School-based oral health promotion initiatives are essential for enhancing children’s and teenagers’ oral health outcomes. However, the long-term efficacy of these initiatives is yet unknown.
Tamalika Chakraborty +7 more
doaj +1 more source