Results 151 to 160 of about 1,080,011 (366)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A Study Of Orbital Fractures In A Tertiary Health Care Center [PDF]

, 2007
A retrospective study of patients with orbital fractures had 48% patients in the age group of 20 – 40 years with male : female ratio of 10:1. Road traffic accidents (71.43%) were the most common cause followed by injury due to fall (20%).
Chhablani, Jay, Chowdary, Somya, Kamath, MG, Kamath, MM, Kamath, Sumana J, Pai, Shobha G   +5 more
core   +1 more source

Smartphone Usage Practices, Preferences and its Perceived Effects in Medical Students at a Tertiary Care Medical College [PDF]

, 2017
Devavrat Harshe, Sagar Karia, Sana Rajani, Anup Bharati, Avinash De Sousa, Nilesh Shah, Priyadarshini Mishra   +6 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Evaluation of Treatment Outcomes and Quality of Life in Patients with Obstructive Sleep Apnea Receiving Oral Appliance Therapy

Journal of Pharmacy and Bioallied Sciences
Background: A frequent sleep condition linked to considerable morbidity and death is obstructive sleep apnea (OSA). Continuous positive airway pressure (CPAP) therapy is not the only noninvasive treatment option for OSA.
T Anjan, Smit Thakkar, Abhishek Jahagirdar, Harshitha Baddam, Swati Manohar Pappulwar, Kunal Jha, M. C. Prashant   +6 more
doaj   +1 more source

The Cost of Negative Perceptions of the Work Environment Among Intermediate Intensive Care Unit Nurses [PDF]

, 2006
This descriptive study assessed the perceptions of the work environment and the retention plans among registered nurses (RNs) who worked in the Intermediate Intensive Care Unit at a tertiary university hospital.
Peralta, Joselyn
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Prevalence of non-compliance to prescribed antihypertensive medication among hypertensive middle-aged adults at a tertiary care hospital, Faisalabad, Pakistan: a descriptive cross-sectional study.

Journal of University Medical & Dental College
BACKGROUND & OBJECTIVE: Uncontrolled hypertension due to non-compliance with prescribed treatment is one of the main reasons for premature illness and mortality in Pakistan.
Sana warraich, Kamran Afzal, Umair Arif , Shagufta Parveen   +3 more
doaj   +1 more source

Candida guilliermondii fungemia: a 12-year retrospective review of antimicrobial susceptibility patterns at a reference laboratory and tertiary care center [PDF]

Jack McHugh, David S. Bayless, Nischal Ranganath, Ryan W. Stevens, Dalton R. Kind, Nancy L. Wengenack, Aditya Shah   +6 more
openalex   +1 more source

A Case Series of Scrub Meningoencephalitis from a Tertiary Care Center in North India

, 2023
Vikas Suri, Harpreet Singh, Kunwer Abhishek Ary, Manisha Biswal, Chirag Ahuja, P Kharbanda, Navneet Sharma   +6 more
openalex   +1 more source