Results 71 to 80 of about 1,080,011 (366)

Central obesity in psoriatic arthritis: associations with disease activity, function, and quality of life in a real-world cohort

open access: yesFrontiers in Medicine
ObjectiveThis study aimed to explore the association between central obesity and disease-specific activity, functional impairment, and patient-reported outcomes (PROMs) in a real-world cohort of individuals with psoriatic arthritis (PsA).MethodsWe ...
Salvatore Corrao   +10 more
doaj   +1 more source

Knowledge and attitude of schoolgirls about illegal abortions in Goma, Democratic Republic of Congo

open access: yesAfrican Journal of Primary Health Care & Family Medicine, 2010
Background: Adolescent sexual activity, early pregnancy, induced abortion and the increase in HIV infection have become major concerns in sub-Saharan Africa and understanding adolescent sexual behaviour remains a challenge.
Lussy J. Paluku   +3 more
doaj   +1 more source

Primary health care at the turn of the millennium : evolution, changes and contrasts [PDF]

open access: yes, 2000
Primary health care is a form of front-line medicine comparable to a valve with a filter. If either is blocked or weak, large amounts of relatively unimportant and trivial material will overflow, causing confusion and delays in the secondary channels ...
Xuereb, Joseph
core  

Malnutrition in a tertiary care hospital

open access: yesIndian Journal of Critical Care Medicine, 2014
Sir, The recent report on malnutrition in a tertiary care hospital is very interesting.[1] Chakravarty et al., concluded that “almost two-fifth of patients admitted were malnourished in this tertiary care hospital and that there is an urgent need to develop a comprehensive nutritional care program in many such Indian intensive care units.”[1] In ...
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Shared care obesity management in 3-10 year old children: 12 month outcomes of HopSCOTCH randomised trial [PDF]

open access: yes, 2013
Objective: To determine whether general practice surveillance for childhood obesity, followed by obesity management across primary and tertiary care settings using a shared care model, improves body mass index and related outcomes in obese children aged ...
Arnup, S.   +9 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Stillbirth in a Tertiary Care Referral Hospital in North Bengal - A Review of Causes, Risk Factors and Prevention Strategies [PDF]

open access: yes, 2011
Background and Aims: Stillbirth is one of the most common adverse outcomes of pregnancy, accounting for half of all perinatal mortality. Each year approximately 4 million stillbirths are reported, with 97% occurring in developing countries. The objective
Bhattacharya, Shritanu   +4 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

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