Results 111 to 120 of about 18,489,886 (307)

An outbreak due to Candida auris with prolonged colonisation and candidaemia in a tertiary care European hospital

Mycoses (Berlin), 2018
Multidrug‐resistant Candida auris has emerged as a cause of insidious hospital outbreaks and complicated infections. We present the analysis of an ongoing C. auris outbreak including the largest published series of C. auris bloodstream infection.
A. Ruiz-Gaitán, A. Moret, María Tasias-Pitarch, Ana I Aleixandre-López, H. Martínez-Morel, E. Calabuig, M. Salavert-Lletí, P. Ramírez, J. López-Hontangas, F. Hagen, J. Meis, J. Mollar‐Maseres, J. Pemán   +12 more
semanticscholar   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Comprehension, viewpoint and precautionary measures against covid-19 among pregnant women attending ante-natal care at a tertiary health facility in Abuja, Nigeria

BMC Pregnancy and Childbirth
Background Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2). Pregnant women are particularly vulnerable to COVID-19 due to physiological and immunological changes in
Fatima Inusa Anga, Habeebah T. Bakare, Chris O. Ifediora, Halima Inusa Anga, Aminat Suleman-Alabi, Amina Ibrahim Shehu, Aisha Mukhtar Dodo, Shefa’atu Shehu, Karima Abdulaziz, Aishat O AbdulMojeed, Tijani Salami   +10 more
doaj   +1 more source

Diabetes Mellitus and Oral Health Status: A Case-Control Study in a Tertiary Care Hospital in Bangladesh

Update Dental College Journal
Introduction: Diabetes is a long-lasting, inflammation-related metabolic disorder which is diagnosed by hyperglycemia. Increased blood glucose level adversely impacts the inflammatory response to periodontium leading to more severe gingivitis and ...
Jesmin Sultana Lucky, Mohammad Anayet Hossain, Dilruba Binte Mostafa, Mohammad Mobashir, Tahnia Binta Nasir, Asadur Rahman, Sadia Parvin   +6 more
doaj   +1 more source

INTERNAL AUDIT QUALITY AND PERFORMANCE OF PUBLIC TERTIARY INSTITUTIONS IN OSUN STATE, NIGERIA

Malete Journal of Accounting and Finance, 2023
Despite the presence of internal audit mechanism in most public tertiary institutions, evidence has shown that most of them have experienced audit failure in recent years with consequential effect on the effectiveness and efficiency in quality of ...
Khadijah Adeola IDOWU, IBRAHIM Jimoh
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Tertiary Education and Economic Growth in Tanzania [PDF]

International Journal of Management, Accounting and Economics
The study examines how tertiary education impact economic growth in Tanzania, time series secondary data spanning from the year 1999 to 2023 were extracted from World Bank database.
Kembo Bwana, Jeremiah Tumaini, Galan Mashenene   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source