Results 71 to 80 of about 18,489,886 (307)

Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana

BMC Psychiatry, 2018
BackgroundDiabetes and depression are both chronic debilitating conditions, and their coexistence has been associated with adverse outcomes. In this study, we investigated the association between glycaemic control and depression in type 2 diabetes (T2DM)
J. Akpalu, Ernest Yorke, J. Ainuson‐Quampah, W. Balogun, K. Yeboah   +4 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Glycemic Control in Patients with Diabetes across Primary and Tertiary Government Health Sectors in the Emirate of Dubai, United Arab Emirates: A Five-Year Pattern

Oman Medical Journal, 2019
Objectives: In the UAE, the comparative prevalence of diabetes is reported as 18.98%, but there are very few studies evaluating glycemic control. Attaining the optimum glycemic control has been a global challenge over the years. However, there is a trend
Fatheya Alawadi, Elamin Abdelgadir, Alaaeldin Bashier, Mohamed Hassanein, Fauzia Rashid, Maryam Alsaeed, Khadija Hafidh, Mohamed Abdellatif Elsayed, Sona Abuelkheir, Muhammad H. Farooqi   +9 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Knowledge and practices of infection control among healthcare workers in a Tertiary Referral Center in North-Western Nigeria

Annals of African medicine, 2016
Background: Healthcare acquired infections (HCAIs) otherwise call nosocomial infection is associated with increased morbidity and mortality among hospitalized patients and predisposes healthcare workers (HCWs) to an increased risk of infections.
G. Iliyasu, F. Dayyab, Z. Habib, A. Tiamiyu, S. Abubakar, M. Mijinyawa, A. Habib   +6 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Navigating an evolving microbial landscape: emerging antimicrobial resistance trends and precision stewardship in Tianjin tertiary hospitals (2021–2023)

Frontiers in Cellular and Infection Microbiology
ObjectiveTo evaluate microbial distribution and antimicrobial resistance (AMR) patterns in clinical isolates from 13 tertiary hospitals and one secondary hospital in Tianjin (2021–2023) to inform precision-driven antimicrobial stewardship and infection ...
Yong-li Wan, Yong-li Wan, Tao Han, Qiang Sun, Donghao Wang, Jun Li, Jun Li, Li-jie Wang, Min Peng, Yin Li, Qing-guo Feng, Chun-guang Liu, Jie Xu, Bin Bao, Mei Su, Zhi-yong Fei, Xu-liang Wang, Xiao-bo Liu   +17 more
doaj   +1 more source

Failure mechanism and supporting measures for large deformation of Tertiary deep soft rock

International Journal of Mining Science and Technology, 2015
The Shenbei mining area in China contains typical soft rock from the Tertiary Period. As mining depths increase, deep soft rock roadways are damaged by large deformations and constantly need to be repaired to meet safety requirements, which is a great ...
Zhibiao Guo, Jiong Wang, Yuelin Zhang
doaj   +1 more source

Assessment of asthma control levels in a tertiary hospital

Saudi Medical Journal
To assess asthma control levels in pediatric patients under 12 years of age attending a tertiary hospital, utilizing the childhood asthma control test (C-ACT) and the test for respiratory and asthma control in kids (TRACK).The study involved 384 children.
Entisar S. Alsafwani, Ayed M. Alenazi, Mansour M. Alqwaiee, Khaled A. BaQais, Adel S. Alharbi, Abdullah S. Al-Shamrani   +5 more
openaire   +2 more sources