Results 71 to 80 of about 10,088,217 (309)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Preparedness for tertiary chemistry: multiple applications of the chemistry competence test for diagnostic and prediction purposes [PDF]
, 2011 This is a post-print of an article published by the Royal Society of Chemistry available at: http://dx.doi.org/10.1039/C1RP90024B.The development of the Chemistry Competence Test was prompted by the extensive curriculum changes in the South African ...
Potgieter, Marietjie +3 more
core +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Oman Medical Journal, 2019 Objectives: A key aspect for the prevention of vascular complications in diabetes is control of hyperlipidemia, and that has always been a global challenge. The prevalence of diabetes mellitus in the UAE is estimated to be 18.98%.
Elamin Abdelgadir +8 more
doaj
Batchelor Institute of Indigenous Tertiary Education reports
, 1999 Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT)
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Frequency of Chikungunya Virus Infection in the Tertiary Care Hospital of Karachi
Journal of Islamic International Medical College, 2021 Objective: To determine the frequency of Chikungunya virus infection in the tertiary care hospital of Karachi during the time from 1stJanuary 2017 till 31st December 2018. Study Design: This was a retrospective cross-sectional study.
Fouzia Zeeshan Khan, Fatima Fasih, Mohammad Sohaib Tauheed, Saba Hassan, Sambreen Zameer
doaj
Media Release - Centre Director Appointed for Creative Industries - August 2009.pdf
, 2015 Media release from the Department of Innovation, Industry, Science, Research and Tertiary Education announcing the appointment of Lisa Colley as Director of the Creative Industries Innovation ...
Department of Innovation, Industry, Science, Research and Tertiary Education
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source