Results 141 to 150 of about 407,264 (267)

Building a National Infection Prevention and Control Programme: the 'Turn Nigeria Orange' Programme, 2019-2023. [PDF]

BMJ Glob Health
Okwor T, Tompkins LK, Gadanya M, Leighty E, Okoro BC, Idris O, Malpiedi P, Ogunsola F.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The differential impact of Diagnosis-Related Groups (DRG) on hierarchical hospitals: an interrupted time series analysis on health expenditure structure. [PDF]

BMC Health Serv Res
Li S, Tu L, Fan R, Zhou X.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Recent Advances in the Characterization of Uropathogenic Escherichia coli Associated With Resistance and Virulence Mechanisms. [PDF]

Cureus
Mahajan MR, Karande GS, Patil SR.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Comparative genomics of hospital-associated vancomycin-resistant <i>Enterococcus faecium</i> from regional tertiary hospitals in Thailand. [PDF]

PeerJ
Sittiyuno C, Yingkajorn M, Chusri S, Surachat K, Chukamnerd A, Sianglum A, Nilsakul J, Mittraparp-Arthorn P, Sianglum W.   +8 more
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Measles outbreak in an occupational setting: challenges to regain elimination status for Spain, 14 January to 11 April 2026. [PDF]

Euro Surveill
Aznar E, Fernández-García A, López-Perea N, Masa-Calles J, Díaz-Sánchez N, Sánchez Carratalá ME, Martín-Aragón Gónzalez E, Cremades Bernabeu I, Maletta Talarico GP, Beso Delgado M, Giner Ferrando E, Guzmán Herrador BR, Soler Crespo P, Sierra Moros MJ, Márquez F, Córdoba Deorador E, Humanes Navarro AM, Boned-Ombuena A, Pascual Del Pobil Ferré MA.   +18 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source