Results 51 to 60 of about 407,199 (267)

Glycemic Control in Patients with Diabetes across Primary and Tertiary Government Health Sectors in the Emirate of Dubai, United Arab Emirates: A Five-Year Pattern

Oman Medical Journal, 2019
Objectives: In the UAE, the comparative prevalence of diabetes is reported as 18.98%, but there are very few studies evaluating glycemic control. Attaining the optimum glycemic control has been a global challenge over the years. However, there is a trend
Fatheya Alawadi, Elamin Abdelgadir, Alaaeldin Bashier, Mohamed Hassanein, Fauzia Rashid, Maryam Alsaeed, Khadija Hafidh, Mohamed Abdellatif Elsayed, Sona Abuelkheir, Muhammad H. Farooqi   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Failure mechanism and supporting measures for large deformation of Tertiary deep soft rock

International Journal of Mining Science and Technology, 2015
The Shenbei mining area in China contains typical soft rock from the Tertiary Period. As mining depths increase, deep soft rock roadways are damaged by large deformations and constantly need to be repaired to meet safety requirements, which is a great ...
Zhibiao Guo, Jiong Wang, Yuelin Zhang
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Navigating an evolving microbial landscape: emerging antimicrobial resistance trends and precision stewardship in Tianjin tertiary hospitals (2021–2023)

Frontiers in Cellular and Infection Microbiology
ObjectiveTo evaluate microbial distribution and antimicrobial resistance (AMR) patterns in clinical isolates from 13 tertiary hospitals and one secondary hospital in Tianjin (2021–2023) to inform precision-driven antimicrobial stewardship and infection ...
Yong-li Wan, Yong-li Wan, Tao Han, Qiang Sun, Donghao Wang, Jun Li, Jun Li, Li-jie Wang, Min Peng, Yin Li, Qing-guo Feng, Chun-guang Liu, Jie Xu, Bin Bao, Mei Su, Zhi-yong Fei, Xu-liang Wang, Xiao-bo Liu   +17 more
doaj   +1 more source

Management for the Children with Otitis Media with Effusion in the Tertiary Hospital [PDF]

Clinical and Experimental Otorhinolaryngology, 2008
ObjectivesRecently, new evidence-based recommendations have been introduced for diagnosing and managing otitis media with effusion (OME) in children. However, there are some difficulties to follow the general guidelines in the tertiary hospitals.
Yun-Hoon Choung, You Ree Shin, Seong Jun Choi, Keehyun Park, Hun Yi Park, Jong Bin Lee, Dong Hee Han, Hison Kahng   +7 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Assessment of asthma control levels in a tertiary hospital

Saudi Medical Journal
To assess asthma control levels in pediatric patients under 12 years of age attending a tertiary hospital, utilizing the childhood asthma control test (C-ACT) and the test for respiratory and asthma control in kids (TRACK).The study involved 384 children.
Entisar S. Alsafwani, Ayed M. Alenazi, Mansour M. Alqwaiee, Khaled A. BaQais, Adel S. Alharbi, Abdullah S. Al-Shamrani   +5 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source