Results 181 to 190 of about 472,872 (267)

Prevalence and Incidence of Nosocomial Infections in a Single Tertiary-Level Neonatal Intensive Care Unit in Oman. [PDF]

Cureus
Albalushi K, Al Saadi A, Al-Rawahi N, Khan A, Saki Malehi A, Alhadrami A, Al-Attraqchi M, Alessai W.   +7 more
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Assessment of Gliflozins prescribing pattern in a United Arab Emirates tertiary-level care hospital. [PDF]

Front Pharmacol
Shenouda W, Thomas D, Nabi O, Zachariah S.   +3 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Clinical Profile and Outcome of Dengue Fever in Medical Intensive Care Unit of a Tertiary Level Hospital: An Observational Study. [PDF]

JNMA J Nepal Med Assoc
Koirala E, Deo GP, Adhikari S, Gauli B, Bajracharya A.   +4 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Risk Factors and Prediction Model for Early-Onset Immune-Related Adverse Events in Pan-Cancer Patients Undergoing Anti-PD-(L)1 Therapy: A Retrospective Study in a Tertiary-Level Hospital. [PDF]

Cancer Med
Jiao P, Xue L, Tan W, Chen Q, Lin S, Song M, Ma C, Zhan J.   +7 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Ocular injuries in patients with orbital fractures in a tertiary level hospital in Tanzania: A cross-sectional study.

Oman J Ophthalmol
Sebasaza FM, Sohal KS, Deoglas DK, Laizer PJ, Sempindu RE.   +4 more
europepmc   +1 more source

Neurological conditions among pediatric patients seeking care at a tertiary level hospital in western Kenya. [PDF]

PLoS One
Oyungu E, McHenry MS, Oduor C, Said J, Kyololo O, von Gaudecker JR.   +5 more
europepmc   +1 more source