Results 41 to 50 of about 1,910,786 (266)
Background:Streptococcus pneumoniae infection among adults, especially in adults over 60 years old in China results in a large number of hospitalizations and a substantial financial burden.
Xiaodong Sun +13 more
doaj +1 more source
The effectiveness of the vero cell inactivated vaccine (CoronaVac®) against severe acute respiratory infection (SARI) caused by SARS-CoV-2 in the real world was assessed.
Teck-Hock Toh +20 more
doaj +1 more source
Analysis of counts for cluster randomized trials: Negative controls and test‐negative designs [PDF]
In cluster randomized trials (CRTs), the outcome of interest is often a count at the cluster level. This occurs, for example, in evaluating an intervention with the outcome being the number of infections of a disease such as HIV or dengue or the number of hospitalizations in the cluster.
Suzanne M. Dufault, Nicholas P. Jewell
openaire +3 more sources
Influenza vaccination is the most effective way of preventing influenza infections but its coverage is extremely low in China. Poor influenza vaccine effectiveness (VE) was reported in the 2014/15 season in some Northern Hemisphere countries with a ...
Chunna Ma +9 more
doaj +1 more source
Immune History and Influenza Vaccine Effectiveness
The imperfect effectiveness of seasonal influenza vaccines is often blamed on antigenic mismatch, but even when the match appears good, effectiveness can be surprisingly low.
Joseph A. Lewnard, Sarah Cobey
doaj +1 more source
Bias correction methods for test-negative designs in the presence of misclassification [PDF]
Abstract The test-negative design (TND) has become a standard approach for vaccine effectiveness (VE) studies. However, previous studies suggested that it may be more vulnerable than other designs to misclassification of disease outcome caused by imperfect diagnostic tests.
Endo, Akira +2 more
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Background: Since 2007, trivalent inactivated influenza vaccine has been provided free-of-charge to older adults aged ≥60 years in Beijing, China, but the data regarding influenza vaccine effectiveness (VE) among these people are very limited so far.
Li Zhang +10 more
doaj +1 more source
Analysis of cluster-randomized test-negative designs: cluster-level methods
SUMMARY Intervention trials of vector control methods often require community level randomization with appropriate inferential methods. For many interventions, the possibility of confounding due to the effects of health-care seeking behavior on disease ascertainment remains a concern.
Nicholas P, Jewell +4 more
openaire +3 more sources
Background: Vaccination is a highly effective strategy for the prevention of enterovirus A71 (EV-A71)—hand, foot, and mouth disease (HFMD). Three inactivated EV-A71 vaccines in China have demonstrated remarkable efficacy against EV-A71-HFMD during ...
Quanman Hu +12 more
doaj +1 more source
Background Influenza is a contagious viral airborne disease that adds to the clinical and economic burden on the healthcare system. It could be prevented substantially by seasonal influenza vaccination.
Roberta Vaikutyte +6 more
doaj +1 more source

