Results 41 to 50 of about 1,910,786 (266)

Effectiveness of 23-Valent Pneumococcal Polysaccharide Vaccine Against Pneumococcal Diseases Among the Elderly Aged 60 Years or Older: A Matched Test Negative Case-Control Study in Shanghai, China

open access: yesFrontiers in Public Health, 2021
Background:Streptococcus pneumoniae infection among adults, especially in adults over 60 years old in China results in a large number of hospitalizations and a substantial financial burden.
Xiaodong Sun   +13 more
doaj   +1 more source

Effectiveness of vero cell inactivated vaccine against severe acute respiratory infections (SARI) in Sibu, Malaysia: A retrospective test-negative design

open access: yesHuman Vaccines & Immunotherapeutics, 2023
The effectiveness of the vero cell inactivated vaccine (CoronaVac®) against severe acute respiratory infection (‎SARI)‎ caused by SARS-CoV-2 in the real world was assessed.
Teck-Hock Toh   +20 more
doaj   +1 more source

Analysis of counts for cluster randomized trials: Negative controls and test‐negative designs [PDF]

open access: yesStatistics in Medicine, 2020
In cluster randomized trials (CRTs), the outcome of interest is often a count at the cluster level. This occurs, for example, in evaluating an intervention with the outcome being the number of infections of a disease such as HIV or dengue or the number of hospitalizations in the cluster.
Suzanne M. Dufault, Nicholas P. Jewell
openaire   +3 more sources

Influenza vaccine effectiveness against medically attended influenza illness in Beijing, China, 2014/15 season

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Influenza vaccination is the most effective way of preventing influenza infections but its coverage is extremely low in China. Poor influenza vaccine effectiveness (VE) was reported in the 2014/15 season in some Northern Hemisphere countries with a ...
Chunna Ma   +9 more
doaj   +1 more source

Immune History and Influenza Vaccine Effectiveness

open access: yesVaccines, 2018
The imperfect effectiveness of seasonal influenza vaccines is often blamed on antigenic mismatch, but even when the match appears good, effectiveness can be surprisingly low.
Joseph A. Lewnard, Sarah Cobey
doaj   +1 more source

Bias correction methods for test-negative designs in the presence of misclassification [PDF]

open access: yesEpidemiology and Infection, 2019
Abstract The test-negative design (TND) has become a standard approach for vaccine effectiveness (VE) studies. However, previous studies suggested that it may be more vulnerable than other designs to misclassification of disease outcome caused by imperfect diagnostic tests.
Endo, Akira   +2 more
openaire   +2 more sources

Moderate influenza vaccine effectiveness against influenza A(H1N1)pdm09 virus and low effectiveness against A(H3N2) virus among older adults during 2013–2014 influenza season in Beijing, China

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Background: Since 2007, trivalent inactivated influenza vaccine has been provided free-of-charge to older adults aged ≥60 years in Beijing, China, but the data regarding influenza vaccine effectiveness (VE) among these people are very limited so far.
Li Zhang   +10 more
doaj   +1 more source

Analysis of cluster-randomized test-negative designs: cluster-level methods

open access: yesBiostatistics, 2018
SUMMARY Intervention trials of vector control methods often require community level randomization with appropriate inferential methods. For many interventions, the possibility of confounding due to the effects of health-care seeking behavior on disease ascertainment remains a concern.
Nicholas P, Jewell   +4 more
openaire   +3 more sources

Effectiveness of EV-A71 Vaccine and Its Impact on the Incidence of Hand, Foot and Mouth Disease: A Systematic Review

open access: yesVaccines
Background: Vaccination is a highly effective strategy for the prevention of enterovirus A71 (EV-A71)—hand, foot, and mouth disease (HFMD). Three inactivated EV-A71 vaccines in China have demonstrated remarkable efficacy against EV-A71-HFMD during ...
Quanman Hu   +12 more
doaj   +1 more source

Influenza vaccine effectiveness in patients hospitalized with severe acute respiratory infection in Lithuania during the 2019–2020 influenza season: a test negative case – control study

open access: yesVirology Journal, 2023
Background Influenza is a contagious viral airborne disease that adds to the clinical and economic burden on the healthcare system. It could be prevented substantially by seasonal influenza vaccination.
Roberta Vaikutyte   +6 more
doaj   +1 more source

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