Results 141 to 150 of about 118,373 (346)
Irradiation test in experimental fast reactor "Joyo"
Masahiro Koyama +2 more
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
[Purposes] With the development of social economy, the proportion of kitchen waste in urban solid waste is increasing. Anaerobic fermentation to produce biomethane is one of the key technologies for the energy utilization of kitchen waste. To address the
ZUO Huan, SUN Chen
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Neutronic peculiarities of the MTRR-SCW reactor as an experimental base for testing advanced light-water reactor technologies [PDF]
Anton S. Lapin +6 more
openalex +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An Experimental Evaluation of the APR1000 Core Flow Distribution Using a 1/5 Scale Model
The experimental data of core flow distribution are indispensable for obtaining licensing and facilitating the design of fluid systems of nuclear reactors.
Kihwan Kim +5 more
doaj +1 more source

