Results 211 to 220 of about 118,373 (346)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Driving Hydrolysis and Acetolysis of Poly(ethylene terephthalate) (PET) by Microwave and Thermal Energy Inputs: A Comparative Study. [PDF]

ACS Omega
Pereira P, Daniszewski AC, Staack M, Salmanzadeh E, Toraman HE, Hu J, Pester CW, Savage PE.   +7 more
europepmc   +1 more source

Parametric experimental tests of steam gasification of pine wood in a fluidized bed reactor

, 2013
L. Vecchione, M. Moneti, Silvia Cocchi, Mauro Villarini, Mario Sisinni, Andrea Micangeli   +5 more
openalex   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Low-Cost IoT-Based Computational System for Real-Time Biogas Monitoring in UASB Reactors Using NDIR Sensors and ESP32. [PDF]

ACS Omega
Nunes FCB, Alves PVA, Gonçalves ABD, Lemos Filho RC, da Silva JGL, Calábria VA, Brito MGSL, de Paula Filho FJ.   +7 more
europepmc   +1 more source

GAS-COOLED REACTOR EXPERIMENTAL EXCURSION TEST. Final Report on Feasibility Studies, August 1, 1964--January 31, 1965.

, 1965
M. Stern, A.D. Baxter, R.C. Dahlberg, G. Melese, M.H. Merrill, W. Thompson   +5 more
openalex   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Hydrostatic Water Displacement Sensing for Continuous Biogas Monitoring. [PDF]

Sensors (Basel)
Habara M, Molitoris J, Jankovičová B, Rybář J, Vachálek J.   +4 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Thermophysical and Rheological Characteristics of CO₂ Hydrate Slurries for Cold Thermal Energy Storage Applications and Engineering Perspectives. [PDF]

Materials (Basel)
Annavajjala SB, Van Dam N, Kosny J.
europepmc   +1 more source