Results 101 to 110 of about 1,599,874 (309)

Identifying Argumentation Skills Using Three Tier Test on Pre-service Physics and Biology Teachers [PDF]

, 2020
Elis Suryani, Y Yusiran, O Hairullah, Siswanto Siswanto, N Nurfathurrahmah, Ariyansyah Ariyansyah   +5 more
openalex   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Origin traceability and adulteration detection of soybean using near infrared hyperspectral imaging

Food Frontiers
Stable isotopes, multi‐elements, metabolic profiles, and integrated spectroscopic fingerprints are priority options for food geographical origin traceability. However, til now, it is still hard to detect adteration with the same one from other geographic
Xue Li, Du Wang, Li Yu, Fei Ma, Xuefang Wang, Dolores Pérez‐Marín, Peiwu Li, Liangxiao Zhang   +7 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Adulteration detection of edible oil by one‐class classification and outlier detection

Food Frontiers
Edible oil adulteration is a mostly practiced phenomenon. However, the traditional discriminant methods fail to detect oil adulteration involving more than one adulterant.
Xinjing Dou, Fengqin Tu, Li Yu, Yong Yang, Fei Ma, Xuefang Wang, Du Wang, Liangxiao Zhang, Xiaoming Jiang, Peiwu Li   +9 more
doaj   +1 more source

Biology and the Gender Gap in Educational Performance: The Role of Prenatal Testosterone in Test Scores [PDF]

, 2018
Anne C. Gielen, Esmée Zwiers
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Prognostic significance of pulmonary function tests in dyskeratosis congenita, a telomere biology disorder [PDF]

, 2019
Neelam Giri, Sandhiya Ravichandran, Youjin Wang, Shahinaz M. Gadalla, Blanche P. Alter, Joseph R. Fontana, Sharon A. Savage   +6 more
openalex   +1 more source