Results 271 to 280 of about 17,965,254 (385)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Activation of B1 B cells by F. tularensis atypical LPS depends on classical complement and C3a. [PDF]

PLoS Pathog
Melo G, Barbosa CHD, Magrini E, Garlanda C, Re F.   +4 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Ten simple rules on how to set up an Innovation Boot Camp for exploitation of research results. [PDF]

PLoS Comput Biol
Hollmann S, Hollmann C, Tobin de Fuentes L, Rodriguez SR, Fredes Y, Garcia-Moyano A, Rørvik C, Regierer B.   +7 more
europepmc   +1 more source

Comparison of the Effects Block and Traditional Schedules Have on the Number of Students Who Are Proficient on the Biology End-of-Course Test in Forty Public High Schools in the State of North Carolina

, 2012
Tonia Anita Bonner
openalex   +1 more source

Preanalytical Impact of Incomplete K2EDTA Blood Tube Filling in Molecular Biology Testing [PDF]

Marco Benati, Laura Pighi, Elisa Paviati, Sara Visconti, Giuseppe Lippi, Gian Luca Salvagno   +5 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Assessing NaV1.7 during tonic firing in pig C-nociceptors. [PDF]

PLoS One
Soares S, Schmelz M, Carr R, Sohns K, Rukwied R.   +4 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Direct-to-Biology Enabled Molecular Glue Discovery. [PDF]

J Am Chem Soc
Hu M, Ochoada J, Actis M, McGowan K, Jarusiewicz JA, Yoshimura S, McGrath L, Neelakantan U, Aggarwal A, Mayasundari A, Young SM, Zhang M, Yang L, Li Y, Mercer S, Babu MM, Fischer M, Young BM, Yang JJ, Nishiguchi G, Shelat AA, Blair DJ.   +21 more
europepmc   +1 more source