Results 341 to 350 of about 17,184,596 (393)

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Alleviating isolation stress in chickens: The benefits of home pen playback and mirrors. [PDF]

PLoS One
Sirovnik J.
europepmc   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Cytochemical analysis of cerebrospinal fluid in tuberculous meningitis versus other etiologies. [PDF]

PLoS One
Hueda-Zavaleta M, de la Torre JCG, Barletta-Carrillo C, Tapia-Sequeiros G, Flores C, Piscoche C, Miranda C, Mendoza A, Sánchez-Tito M, Benites-Zapata VA.   +9 more
europepmc   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Field validation and application of the luminex triplex HIV assay to estimate HIV prevalence and HIV-1 incidence in Nigeria. [PDF]

PLOS Glob Public Health
Yufenyuy EL, Akanbi OA, Shanmugam V, Decker-Pulice K, Vuong J, Detorio M, Zheng A, Bassey O, Abubakar AG, Akinmulero O, Esiekpe M, Thomas A, Bichi IA, Tamunonengiyeofori I, Ugwu C, Erasogie E, Nwachukwu W, Mba N, Agala N, Bronson M, Patel HK, Iriemenem NC, Greby S, Okoye MI, Swaminathan M, Parekh BS, Ihekweazu C.   +26 more
europepmc   +1 more source

Traumatic injury leads to ovarian cell death and reproductive disturbances in Drosophila melanogaster. [PDF]

Biol Open
Dixon CT, Yang P, McCall K.
europepmc   +1 more source

Association of adenylate cyclase activity in vasopressor-type neurally mediated syncope based on the α2b-AR gene. [PDF]

PLoS One
Komiyama T, Ayabe K, Orita K, Sasaki A, Kitamura Y, Matsuzawa H, Yamashita T, Nagata E, Kanatani Y, Yoshioka K.   +9 more
europepmc   +1 more source

Short naps improve subsequent learning in a high school setting. [PDF]

NPJ Sci Learn
Vidal V, Pretel MR, Capurro L, Tassone LM, Moyano MD, Malacari RG, Brusco LI, Ballarini FM, Forcato C.   +8 more
europepmc   +1 more source

Metabolic improvement after exercise training in children with obesity: Possible role of the six-minute walking test. [PDF]

PLoS One
Giovanelli L, Bernardelli G, Facchetti S, Malacarne M, Vandoni M, Carnevale Pellino V, Zuccotti G, Calcaterra V, Lucini D.   +8 more
europepmc   +1 more source