Results 251 to 260 of about 10,534,072 (354)

A new type of constitutional hyperbilirubinemia with unconjugated bilirubin-A case of nonhemolytic hyperbilirubinemia with marked retention of sulfobromophthalein test

, 1980
Masaji Nambu, Chikako Ueda, Koki YOSHIMURA, Ryuichi Sakita, Sanpei HISHINUMA, Hiroshi Ueyama, Ayako Morikawa, Masatake Takagi, Hideo UEDA, Akira Asahara, Hiroshi Ishihara, Yuji YAMASHIRO, Norio Kobayashi, Hiroyuki Kuroda, Toshihiko Namihisa   +14 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Civil society activism for Africa's vaccine and local manufacturing agenda: Can mpox be the test case? [PDF]

PLOS Glob Public Health
Ndembi N, Kimathi G, Prabhala A, Kiarie J.   +3 more
europepmc   +1 more source

Joint Geosat-NASA/JPL Test Case Program: Field Evaluation of Future Geological Satellite Remote-Sensing Systems: ABSTRACT

, 1985
Frederick B. Henderson
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

The Role of Double Excitations in Exciton Dynamics of Multiazobenzenes: Trisazobenzenophane as a Test Case. [PDF]

J Phys Chem Lett
Titov E.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Toward the identification of cyano-astroCOMs via vibrational features: benzonitrile as a test case. [PDF]

Front Chem
Xu Y, Biczysko M.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Comparing conventional and phytoscreening methods to detect subsurface chemical contaminants: A test case of volatile organic compounds in an urban setting. [PDF]

Environ Pollut
O'Leary BF, Miller CJ, Selegean K, Hood GR.   +3 more
europepmc   +1 more source