Results 271 to 280 of about 10,534,072 (354)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Editor's Spotlight/Take 5: How Can the Environmental Impact of Orthopaedic Surgery Be Measured and Reduced? Using Anterior Cruciate Ligament Reconstruction as a Test Case. [PDF]

Clin Orthop Relat Res
Leopold SS.
europepmc   +1 more source

Prueba de inclinación (Head-up Tilt Test), lecciones aprendidas en 564 casos consecutivos: Lessons Learned from 564 Consecutive Cases

, 2012
Oswaldo Gutiérrez-Sotelo, Yorleny Alfaro-Badilla   +1 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Opportunities and challenges for identifying undiagnosed Rare Disease patients through analysis of primary care records: long QT syndrome as a test case. [PDF]

J Community Genet
Evans W, Akyea RK, Simms A, Kai J, Qureshi N.   +4 more
europepmc   +1 more source

Super-selective Balloon Test Occlusion of the Posterior Communicating Artery in the Treatment of a Posterior Cerebral Artery Fusiform Aneurysm: a Case Report

, 2016
Makoto Isozaki, Hiroshi Arai, Hiroyuki Neishi, Ryuhei Kitai, Ken‐ichiro Kikuta   +4 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Tree-based scan statistics to generate drug repurposing hypotheses: a test case using sodium-glucose cotransporter-2 inhibitors. [PDF]

Am J Epidemiol
Tan GSQ, Maro JC, Wang SV, Toh S, Morton JI, Ilomäki J, Wong J, Li X.   +7 more
europepmc   +1 more source

Minimal Test Case Generation for Effective Program Test using Control Structure Methods and Test Effectiveness Ratio

, 2011
Swathi. J.N, Sumaiya Thaseen I., S. Sangeetha   +2 more
openalex   +1 more source