Results 151 to 160 of about 5,036,684 (298)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Modeling and assessing multiplicative operation sense—validation of a test instrument for 5th grade

Frontiers in Education
IntroductionA considerable number of students enter secondary school with fundamental gaps in basic mathematical skills, particularly in their understanding of operations related to multiplication and division. The conceptual understanding of operations -
Eva Schultheis, Timo Leuders, Frank Reinhold, Katharina Loibl   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Exploring GenAI-Powered Listening Test Development

Languages
The advent of Generative Artificial Intelligence (GenAI) has ushered in a transformative wave within the field of language education. However, the applications of GenAI are primarily in language teaching and learning, with assessment receiving much less ...
Junyan Guo
doaj   +1 more source

MOSAIC Amphibious Test Range Development and Deployment

, 2023
The MOSAIC approach is to package mobile, standalone hypersonic test capability into ISO standard shipping containers that can be placed on many different types of leased ships, or be deployed on land at any desired test location.
Debbaneh, William, Goins, Joshua
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Pre-service teachers’ situation-specific skills regarding classroom management in physical education: validation of a video-based test instrument

Frontiers in Education
IntroductionSituation-specific skills, comprising Perception, Interpretation, and Decision-making (PID), are considered a central facet of teachers’ professional competence, linking professional knowledge to observable performance.
Eric Jeisy, Clemens Berthold, Matthias Baumgartner   +2 more
doaj   +1 more source

Large scale production and characterization of SARS-CoV-2 whole antigen for serological test development. [PDF]

J Clin Lab Anal, 2021
Cerutti H, Ricci V, Tesi G, Soldatini C, Castria M, Vaccaro MN, Tornesi S, Toppi S, Verdiani S, Brogi A.   +9 more
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Creation of an Expert Curated Variant List for Clinical Genomic Test Development and Validation: A ClinGen and GeT-RM Collaborative Project. [PDF]

J Mol Diagn, 2021
Wilcox E, Harrison SM, Lockhart E, Voelkerding K, Lubin IM, ClinGen Expert Panels, Rehm HL, Kalman LV, Funke B.   +8 more
europepmc   +1 more source