Results 101 to 110 of about 187,525 (244)

Thermal improvement of existing dwellings [PDF]

open access: yes, 2005
This report describes the outcome from a study to determine the impact of energy efficiency measures applied to the Scottish housing stock. Assuming conventional property type classifications, the present performance of the housing stock is quantified ...
Clarke, Joseph Andrew   +5 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Igualación Lineal de Tres Versiones del Examen de Habilidades y Conocimientos Básicos (EXHCOBA)

open access: yesRevista Iberoamericana de Evaluación Educativa, 2016
El método estadístico de igualación lineal implica cambiar la escala de manera que se modifique la media y la desviación estándar, mientras se conserva exactamente la forma de la distribución y, en consecuencia las posiciones relativas de los individuos ...
Luz Elena Antillón   +2 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Isospectrality of spherical MHD dynamo operators: pseudo-Hermiticity and a no-go theorem

open access: yes, 2002
The isospectrality problem is studied for the operator of the spherical hydromagnetic alpha^2-dynamo. It is shown that this operator is formally pseudo-Hermitian (J-symmetric) and lives in a Krein space.
Anderson   +29 more
core   +4 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Item response theory in educational assessment and evaluation

open access: yesMesure et Évaluation en Éducation, 2008
Item response theory provides a useful and theoretically well-founded framework for educational measurement. It supports such activities as the construction of measurement instruments, linking and equating measurements, and evaluation of test bias and ...
Cees A.W. Glas
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Talent Investments Pay Off: Executive Briefing - Advocate Health Care Realizes Returns for Investments in Education Assistance [PDF]

open access: yes, 2016
An analysis of Advocate Health Care's Education Assistance Program (EAP), conducted by Accenture and partner Lumina Foundation, shows a 4-percent return on every dollar invested in tuition assistance for the health system.

core  

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