Results 81 to 90 of about 6,985,568 (304)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Development and validation of a clinical practice guidelines implementability assessment tool (CPG-IAT) based on the COSMIN framework

Implementation Science
Introduction We define guideline implementability as the characteristics of the guideline that reflect the extent to which it is likely to be adopted in clinical practice. Improving the intrinsic quality (e.g., context, format, language etc.) of clinical
Dongmei Zhong, Gregory A. Aarons, Yaolong Chen, Nan Yang, Wenjun He, Run Wang, Jiawen Tang, Yimin Wu, Zizhen Huang, Dong Roman Xu   +9 more
doaj   +1 more source

A Hierachical Infrastrucutre for SOC Test Management [PDF]

, 2003
HD2BIST - a complete hierarchical framework for BIST scheduling, data-patterns delivery, and diagnosis of complex systems - maximizes and simplifies the reuse of built-in test architectures.
Zorian Y., Zorian, Y., Benso, Alfredo, Prinetto, Paolo Ernesto, Di Carlo, Stefano   +4 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Oral toxicity of small microplastic of polyamide assessed by a standardized guideline study

Microplastics and Nanoplastics
There is a dire lack of standardized in vivo studies investigating the human hazard by microplastics by OECD test guidelines. The lack of suitable test materials contributes to this situation.
Roland Buesen, Stefanie Vogel, Tizia Thoma, Volker Strauss, Sibylle Gröters, Kathrin Becker, Frank Müller, Till Gründling, Patrizia Pfohl, Amelie Vogel, Andrea Haase, Wendel Wohlleben   +11 more
doaj   +1 more source

KRG and its major ginsenosides do not show distinct steroidogenic activities examined by the OECD test guideline 440 and 456 assays. [PDF]

J Ginseng Res, 2023
Lee N, Lee JH, Won JE, Lee YJ, Hyun SH, Yi YD, In G, Han HD, Lee Y.   +8 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Development and validity of an innovative test to assess guideline-consistent clinical reasoning by physical therapists in stroke rehabilitation

Journal of Rehabilitation Medicine, 2019
Objective: To evaluate the validity of a script concordance test to assess guideline-consistent clinical reasoning by physical therapists in stroke rehabilitation, and to identify critical features of physical therapists specializing in ...
Nicoline M. Otterman, Marjo Maas, Sven K. Schiemanck, Philip van der Wees, Gert Kwakkel   +4 more
doaj   +1 more source

Diagnosis of Food Allergy Based on Oral Food Challenge Test

Allergology International, 2009
Diagnosis of food allergy should be based on the observation of allergic symptoms after intake of the suspected food. The oral food challenge test (OFC) is the most reliable clinical procedure for diagnosing food allergy.
Komei Ito, Atsuo Urisu
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source