Results 31 to 40 of about 6,681,031 (252)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Journal of Materials Research and Technology, 2023 Recent developments in additive manufacturing technology have enabled the precise fabrication of intricate lattice materials, also known as metamaterials, for various engineering applications, particularly those involving dynamics.
Chukwugozie J. Ejeh +3 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
, 2021 This is a sample submission generated by Vireo to test the repository deposit features.Test ...
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Generative Models for Periodicity Detection in Noisy Signals
Clocks & SleepWe present the Gaussian Mixture Periodicity Detection Algorithm (GMPDA), a novel method for detecting periodicity in the binary time series of event onsets.
Ezekiel Barnett +4 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Numerical Test of the PBA Periodogram and Period Analysis of FRB 20190520B
The Astrophysical JournalThe periodicity of repeating fast radio bursts (FRBs) is crucial for understanding their origins and usually requires appropriate methods to identify. In a recent paper, we developed the Phase-folding probability Binomial Analysis (PBA) periodogram and ...
Ronghao Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Nantong Daxue xuebao. Ziran kexue ban, 2020 The pressure fluctuations of the centrifugal pumps have a great influence on the safe and stable operation of centrifugal pumps. In order to reveal the pressure fluctuations characteristics of the centrifugal pump at different rotational speed, a single ...
TAN Linwei;NIU Guoping;SHI Weidong;SHI Zhouhao;CHEN Cheng
doaj +1 more source