Results 121 to 130 of about 20,253,687 (309)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Journal of Accounting and Investment, 2016 This research has a purpose to know the influence of interest, profit sharing, and LQ 45 to funding in Indonesian Syariah Bank Period 2006-2008. All trials in this research use the help of SPSS program. The trial of quality of data use Classic Assumption
Yustitia Agil Reswari, Ahim Abdurahim
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
A Comparing Robust Wilks’ statistics in Multivariate Multiple Linear Regression
Journal of Kufa for Mathematics and ComputerIn multivariate linear regression, the classical Wilks’ statistic is the most used method to test hypotheses, which is extremely responsive to the effect of outliers.
Thamer, Abdullah A. Ameen
doaj +1 more source
Likelihood Ratio Testing for Cointegration Ranks in I(2) Models. [PDF]
This paper presents the likelihood ratio (LR) test for the number of cointegrating and multi-cointegrating relations in the I(2) vector autoregressive model. It is shown that the asymptotic distribution of the LR test for the (multi-) cointegration ranks
Anders Rahbek, Heino Bohn Nielsen
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A SAS/IML algorithm for an exact permutation test
GMS Medizinische Informatik, Biometrie und Epidemiologie, 2009 An algorithm written in SAS/IML is presented that can perform an exact permutation test for a two-sample comparison. All possible permutations are considered.
Neuhäuser, Markus +2 more
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Monotonicity of Chi-square Test Statistics [PDF]
This paper establishes monotonicity of the chi-square test statistic. As the more efficient parameter estimator is plugged into the test statistic, the degrees of freedom of the resulting chi-square test statistic monotonically increase.
Keunkwan Ryu
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source