Results 21 to 30 of about 67,805 (249)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Geometric scalar theory of gravity

open access: yes, 2013
We present a geometric scalar theory of gravity. Our proposal will be described using the "background field method" introduced by Gupta, Feynman and others as a field theory formulation of general relativity. We analyze previous criticisms against scalar
Bittencourt, E.   +5 more
core   +1 more source

OPTIS - a satellite-based test of Special and General Relativity [PDF]

open access: yes, 2001
A new satellite based test of Special and General Relativity is proposed. For the Michelson-Morley experiment we expect an improvement of at least three orders of magnitude, and for the Kennedy-Thorndike experiment an improvement of more than one order ...
  +14 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Resource Letter PTG-1: Precision Tests of Gravity

open access: yes, 2010
This resource letter provides an introduction to some of the main current topics in experimental tests of general relativity as well as to some of the historical literature. It is intended to serve as a guide to the field for upper-division undergraduate
Will, Clifford M.
core   +1 more source

Causality and the speed of sound [PDF]

open access: yes, 2007
A usual causal requirement on a viable theory of matter is that the speed of sound be at most the speed of light. In view of various recent papers querying this limit, the question is revisited here.
A. Ranfagni   +17 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Gravity and the Quantum: Are they Reconcilable?

open access: yes, 2005
General relativity and quantum mechanics are conflicting theories. The seeds of discord are the fundamental principles on which these theories are grounded.
Aldrovandi, R.   +2 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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