Testes size, testosterone production and reproductive behaviour in a natural mammalian mating system [PDF]
1. Testosterone (T) is a key mediator in the expression of numerous morphological and behavioural traits in mammals, but the factors underlying individual variation in circulating T levels are poorly understood. 2.
Monfort, Steven L. +5 more
core +5 more sources
Super-Multiplexed Label-Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation. [PDF]
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Li J +23 more
europepmc +2 more sources
WFS1 Deficiency Impairs PIAS4-Associated SUMOylation and Increases Ubiquitin-Mediated Spermatogenesis-Related Protein Degradation Leading to Testicular Male Infertility. [PDF]
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Tian Y +14 more
europepmc +2 more sources
A case of abdominal migration of the testes presenting with azoospermia [PDF]
31-year-old male was referred to our hospital due to azoospermia. Physical examination revealed impal-pable testes in the scrotum, and operative scar presented at lower abdominal midline.
Sugie, Miho +3 more
core +1 more source
BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells. [PDF]
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Li X +8 more
europepmc +2 more sources
The Use of Cognitive Maps for Requirements Elicitation in Product Development
This article approaches Engineering Requirements concepts and proposes the use of cognitive maps as support to the problem identification of the stakeholders during the requirements elicitation process.
Raquel Dias +3 more
doaj +1 more source
Canine and Feline Testicular Preservation
The increased interest in breeding dogs and cats and their use as models for other canids and felids demand research to improve reproductive techniques. Among them, testicular cryopreservation stands out.
Lúcia Daniel Machado da Silva
doaj +1 more source
Prenatal and Postnatal Exposure to Cell Phone Radiation and its Possible Impact on the Development of Albino Rat Testicular Tissue Light and Electron Microscopic Study [PDF]
Introduction: Perinatal periods are critical phases in the development of testis, and it is sentient to the surrounding environmental pollutants. Electromagnetic radiation (EMR) exposure as a consequence of excessive use of cell phones might be one of ...
Abdelmonem Hegazy +3 more
doaj +1 more source
Testicular regression occurs during the non-breeding season in many mammals. This affects spermatogenesis, resulting in decreased or arrested activity. Both lead to a decrease or cessation in sperm production.
Ester Beltrán-Frutos +5 more
doaj +1 more source
The effects of coenzyme q10 on testes of rats with diabetes induced by streptozotocin [PDF]
Aim: In this study, it was aimed to determine the effect of CoQ10 on testes in streptozotocin (STZ) induced diabetic rats. Materials and Methods: In this study, thirty-four adult male Wistar Albino rats were used.
Tuğba Özaydın +2 more
doaj

