Results 51 to 60 of about 22,890 (305)
Advanced Science, EarlyView.Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Advanced Science, EarlyView.Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
Advanced Science, EarlyView.eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu +12 more
wiley +1 more source
Bihdād, 2020 Background: Vitamin D is an essential vitamin of body that helps to grow and strengthen the bones. In the present study, the Protective effect of vitamin D on function and testicular tissue in adult rat treated with thioacetamide was studied.
Azam Nourozi, Mehrdad Shariati
doaj
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2009 Avaliaram-se os efeitos da geleia real sobre os parâmetros morfofisiológicos testiculares de camundongos (Mus musculus). Utilizaram-se 57 machos Swiss, com quatro meses de idade, distribuídos aleatoriamente em seis tratamentos: T1: solução fisiológica ...
A.C.T. Morais +5 more
doaj +1 more source
Advanced Science, EarlyView.Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen +14 more
wiley +1 more source
Histologia del testicle i l'epidídim
, 2020 Projecte: 2014PID-UB/012Vídeo breu de la histologia del testicle i l'epidídim, on es mostren les estructures que es poden visualitzar en el mòdul Histoflash del testicle i ...
Martín Venegas, Raquel +6 more
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Advanced Science, EarlyView.In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu +16 more
wiley +1 more source
A case of torsion of the undescended testicle [PDF]
, 1986 An eight-year-old boy was admitted to our hospital with the chief complaint of pain and swelling of the left inguinal testicle which had occurred 4 days earlier.
伊藤, 康久 +2 more
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