Results 111 to 120 of about 51,797 (303)

Doxorubicin Affects Testicular Lipids with Long-Chain (C18-C22) and Very Long-Chain (C24-C32) Polyunsaturated Fatty Acids [PDF]

, 2007
Doxorubicin disrupts spermatogenesis by causing apoptosis of spermatogonia and primary spermatocytes. The aim of this study was to examine the effect of this agent on adult rat testicular lipids and their fatty acids.
Aveldaño, Marta Isabel, Maldonado, Eduardo N., Zanetti, Samanta Romina   +2 more
core   +1 more source

Chrysin Mitigates Acetamiprid‐Induced Testicular Injury in Mice via Suppression of Endoplasmic Reticulum Stress and Inflammation

Environmental Toxicology, EarlyView.
ABSTRACT Acetamiprid (ACP) is a neonicotinoid pesticide that is extensively utilized for the management of insect populations, but its toxic effects on the male reproductive system have become a source of concern. Chrysin (CHR) is a natural flavone found in many plants and bee products, including honey and propolis.
Selim Demir, Nihal Turkmen Alemdar, Esin Yulug, Ali Kulaber, Elif Ayazoglu Demir, Nadire Sevdenur Erdogan, Ahmet Mentese, Yuksel Aliyazicioglu   +7 more
wiley   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Association of ghrelin and leptin with reproductive hormones in constitutional delay of growth and puberty

Reproductive Biology and Endocrinology, 2010
Background Constitutional delay of growth and puberty (CDGP) is a variation of the onset and timing of pubertal development without a defined endocrine abnormality.
El hawary Amany K, Abdel Aal Ibrahim A, El-Eshmawy Mervat M   +2 more
doaj   +1 more source

Testicular Anti-Müllerian Hormone: Clinical Applications in DSD

Seminars in Reproductive Medicine, 2012
Male fetal sexual differentiation of the genitalia is driven by Leydig cell-secreted androgens and Sertoli cell-secreted anti-Müllerian hormone (AMH). Disorders of sex development (DSD) may be due to abnormal morphogenesis of genital primordia or to defective testicular hormone secretion or action. In dysgenetic DSD, due to an early fetal-onset primary
Josso, Nathalie, Rey, Rodolfo Alberto, Picard, Jean-Yves   +2 more
openaire   +3 more sources

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

ATRA-mediated RAR-α activation attenuates acrylamide-induced testicular toxicity

Scientific Reports
Acrylamide (ACR) is an environmental reproductive toxicant with unclear testicular toxicity mechanisms. Retinoids are a group of vitamin A-related compounds that function by activating retinoid receptors.
Hamada Ahmed Mokhlis, Mohammed Helmy Rashed, Ibrahim Ghalib Saleh, Mahmoud Gomaa Eldeib, Ahmed A. El-Husseiny, Emad Gamil Khidr, Maher H. Gomaa, Hesham S. Gad, Mohamed R. Elnagar, Mahmoud Mohamed Mokhtar, Ahmed Aglan   +10 more
doaj   +1 more source

Source of the Testicular Hormone.

Experimental Biology and Medicine, 1928
In 1903 Ancel and Bouin1 published the theory that the interstitial cells of the testis (the cells of Leydig) produced the testicular hormone. The theory was based upon 4 main premises, as follows: Animals remain sexually active (a) after vasectomy, (b) when they possess only cryptorchid testes, (c) when their testes have been exposed to Roentgen rays ...
openaire   +1 more source

Advances in cholesterol and lipoproteins detection for healthcare: A review

VIEW, EarlyView.
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta, Somayeh Fardindoost, Azadeh Abdi, Kaveh Yazdani, Longfei Yin, Syamak Farajikhah, Mina Hoorfar, Fariba Dehghani   +7 more
wiley   +1 more source

Testicular hormones mediate robust sex differences in impulsive choice in rats. [PDF]

Elife, 2020
Hernandez CM, Orsini C, Wheeler AR, Ten Eyck TW, Betzhold SM, Labiste CC, Wright NG, Setlow B, Bizon JL.   +8 more
europepmc   +1 more source