Results 31 to 40 of about 51,797 (303)

Ochratoxin A: In Utero Exposure in Mice Induces Adducts in Testicular DNA [PDF]

, 2010
Ochratoxin A (OTA) is a nephrotoxin and carcinogen that is associated with Balkan endemic nephropathy and urinary tract tumors. OTA crosses the placenta and causes adducts in the liver and kidney DNA of newborns.
Jamie E. Jennings-Gee, Mariana Tozlovanu, Richard Manderville, Mark Steven Miller, Annie Pfohl-Leszkowicz, Gary G. Schwartz, O’Brien, Pfohl-Leszkowicz, Reddy, Krogh, Stoev, Chernozemsky, Pfohl-Leszkowicz, Castegnaro, Huyghe, Schwartz, Ueta, Raymond, Mantle, Mantle, Pfohl-Leszkowicz, Petkova-Bocharova, Petkova-Bocharova, Satoh, Manderville, Faucet, Gillman, Molinié, Nguyen, Petkova-Bocharova, Faucet-Marquis, Frenette, Pfohl-Leszkowicz, Mantle, Pfohl-Leszkowicz, Pinelli, El Adlouni, Petkova-Bocharova, Pfohl-Leszkowicz, Verma, Kamataki, Gustafsson, Atanasova, Pfohl-Leszkowicz, Pfohl-Leszkowicz, Pfohl-Leszkowicz, Dimitrov, Møller, Bay, Bose, Solti, Patil, Lei   +52 more
core   +3 more sources

Genetics and Hormones in Testicular Descent

HORMONES, 2003
Testicular descent is an essential part of normal male sexual development. Any anomaly that disrupts normal testicular descent will be clinically evident as cryptorchidism. Several factors, such as Hoxa-10, epidermal growth factor (EGF), calcitonin gene-related peptide (CGRP), and hormones, especially androgens and insulin-like factor 3 (INSL-3), have ...
Marko, Kaleva, Jorma, Toppari
openaire   +2 more sources

Chronic exposure of adult male Wistar rats to bisphenol A causes testicular oxidative stress: Role of gallic acid

Endocrine Regulations, 2020
Objectives. Bisphenol A (BPA) has been reported that among other male reproductive dys-functions, it can cause marked estrogenic effects including alteration in serum hormones as well as testicular lesions in exposed animals.
Olukole Samuel Gbadebo, Ola-Davies Eunice Olufunke, Lanipekun Damilare Olaniyi, Oke Bankole Olusiji   +3 more
doaj   +1 more source

Developmental changes in the histological structure of the testes, and testosterone profiles in male guinea fowls (Numida meleagris) [PDF]

, 2017
Owing to the paucity of information on the reproductive biology of guinea fowls, a study involving a total of 66 males was conducted, and documented the developmental changes in histological structure of the testes of guinea cocks from hatching until ...
Abdul-Rahman, Iddriss I., Jeffcoate, Ian A., Obese, Frederick Y.   +2 more
core   +1 more source

Omega-3 fatty acid ameliorates bisphenol F-induced testicular toxicity by modulating Nrf2/NFkB pathway and apoptotic signaling

Frontiers in Endocrinology, 2023
IntroductionBisphenol F (BPF) has been shown to disrupt testicular functions via perturbation of testicular redox balance, while omega-3 fatty acid (O3FA) has been established to exert antioxidant and anti-inflammatory activities.
Adeyemi Fatai Odetayo, Adeyemi Fatai Odetayo, Wale Johnson Adeyemi, Luqman Aribidesi Olayaki   +3 more
doaj   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Evaluation of the beneficial impact of pomegranate seed extract against the testicular toxicity induced by mercuric chloride in male rats [PDF]

Journal of Medical and Life Science
Mercury (Hg) is among the most hazardous heavy metals that adversely affect testicular tissue. Mercuric chloride (HgCl₂) is one of the most poisonous types of mercury.
Abdelalim Gadallah, Enas Sohsah, Mona Soliman, Samah Mekhaimer   +3 more
doaj   +1 more source

GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation.

PLoS Genetics, 2020
Urogenital tract abnormalities are among the most common congenital defects in humans. Male urogenital development requires Hedgehog-GLI signaling and testicular hormones, but how these pathways interact is unclear.
Anbarasi Kothandapani, Samantha R Lewis, Jessica L Noel, Abbey Zacharski, Kyle Krellwitz, Anna Baines, Stephanie Winske, Chad M Vezina, Elena M Kaftanovskaya, Alexander I Agoulnik, Emily M Merton, Martin J Cohn, Joan S Jorgensen   +12 more
doaj   +1 more source

Update on male reproductive endocrinology. [PDF]

, 2018
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core   +1 more source