Results 71 to 80 of about 51,797 (303)

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

Single-cell RNA sequencing uncovers abnormal Sertoli-cell elevation and testicular niche impairment in the transfemales’s testis

Cell & Bioscience
Background Transgender women (transfemales) often undergo gender-affirming hormone therapy (GAHT). However, the testicular impacts of feminising hormones present heterogeneity due to the complexity of testicular regulatory mechanisms.
Jun Yu, Longfei Hu, Huixia Li, Xiaofeng Li, Chaoye Ma, Ting Jiang, Yongxin Liu, Xue Wang, Xia Li, Liandong Zuo, Haocheng Lin, Wenming Xu, Yiwen Zhou, Yang Liu, Hao Chen   +14 more
doaj   +1 more source

Testicular Macrophages: Isolation, Characterization and Hormonal Responsiveness [PDF]

Biology of Reproduction, 1983
Macrophages were isolated from rat testes with trypsin treatment and established in culture using a differential attachment technique. The cells were maintained in culture in Medium 199 at 32 degrees C. The cells were then characterized for their ability to express traditional immunological function as well as to secrete lactate under the regulation of
J B, Yee, J C, Hutson
openaire   +2 more sources

Protective Effects of Fenugreek and Stevia Extracts on Dexamethasone‐Induced Testicular Damage in a Rat Model

Food Safety and Health, EarlyView.
Fenugreek and stevia extracts protect against dexamethasone‐induced testicular damage in male rats by enhancing antioxidant defenses, improving sperm quality, and restoring hormonal balance, highlighting their potential as natural therapeutics for preventing corticosteroid‐induced reproductive toxicity.
Mosab Gad, Medhat Ibrahim A. Omar, Mohammed I. Elkhateeb, Ahmed A. Zaky   +3 more
wiley   +1 more source

Effect of Light-Dark Cycle Misalignment on the Hypothalamic-Pituitary-Gonadal Axis, Testicular Oxidative Stress, and Expression of Clock Genes in Adult Male Rats

International Journal of Endocrinology, 2020
This study investigated the influence of circadian misalignment on the male reproductive system. Adult Sprague-Dawley male rats were exposed to prolonged light (20 h light : 4 h dark) or prolonged darkness (4 h light : 20 h dark) for 12 consecutive weeks.
Amira Moustafa
doaj   +1 more source

Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]

, 1992
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Gerbes, Alexander L., Hörmann, Rudolf, Jüngst, Dieter, Mann, Klaus, Spöttl, Gerald   +4 more
core  

Endocrine and metabolic evaluation of classic Klinefelter syndrome and high-grade aneuploidies of sexual chromosomes with male phenotype: are they different clinical conditions? [PDF]

, 2018
Klinefelter syndrome (KS) is the most common sex chromosome aneuploidy in males. As well as classic KS, less frequent higher-grade aneuploidies (HGAs) are also possible.
Anzuini, Antonella, Granato, Simona, Lenzi, Andrea, Mileno, Benedetta, Radicioni, Antonio F, Rossi, Fabio, Spaziani, Matteo, Tahani, Natascia   +7 more
core   +1 more source

Endocrine Disrupting Chemicals Interfere With Leydig Cell Hormone Pathways During Testicular Descent in Idiopathic Cryptorchidism

Frontiers in Endocrinology, 2019
Cryptorchidism, a frequent genital malformation in male newborn, remains in most cases idiopathic. On the basis of experimental, epidemiological, and clinical data, it has been included in the testicular dysgenesis syndrome and believed to be influenced,
Patrick Fénichel, Patrick Fénichel, Nicolas Chevalier, Nicolas Chevalier, Najiba Lahlou, Patrick Coquillard, Kathy Wagner-Mahler, Michel Pugeat, Patricia Panaïa-Ferrari, Françoise Brucker-Davis, Françoise Brucker-Davis   +10 more
doaj   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Adverse Effect of COVID-19 on Male Fertility and Male Sex Hormones

Medical Journal of Babylon
Background: Coronaviruses (CoVs) cause infections in human testes and may affect seminal fluid analysis (SFA) because the testes widely express angiotensin-converting enzyme 2 receptors.
Salam Abd-Elameer Yahya, Adil Ibrahim Al-Najjar, Muhammed Ibrahim Muhsun   +2 more
doaj   +1 more source