Results 161 to 170 of about 22,081 (298)

Commentary: Management of non-palpable subcentimeter testicular incidentalomas. [PDF]

Front Oncol
You J, Li G.
europepmc   +1 more source

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

The FEBS Journal, EarlyView.
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang, Min Peng, Gerson Dierley Keppeke, Li‐Kuang Tsai, Ziheng Zhang, Li‐Mei Pai, Li‐Ying Sung, Ji‐Long Liu   +7 more
wiley   +1 more source

Unusual Presentation of Metastatic Testicular Mixed-Germ Cell Tumor with Intracardiac Extension: A Case Report. [PDF]

J Clin Med
Rojas-Cadena M, Rodríguez-Arcentales F, Lata W, Sacoto KM, Guerrero L, Narváez Inca K, Arias-Intriago M, Ortiz-Prado E, Izquierdo-Condoy JS.   +8 more
europepmc   +1 more source

Immune evaluation with skin testing.A study of testicular, prostatic, and bladder neoplasms [PDF]

, 1976
Paul F. Schellhammer, R B Bracken, Michael A. Bean, Carl Pinsky, Willet F. Whitmore   +4 more
openalex   +1 more source

Adverse impact of acute Toxoplasma gondii infection on human spermatozoa

The FEBS Journal, EarlyView.
Toxoplasma gondii tachyzoites injected intraperitoneally crossed the blood‐testes barrier, appearing in testes/epididymis by day 6 post‐infection. In vitro exposure caused increased sperm necrosis/apoptosis and structural damage to heads/tails. Immunofluorescence and SEM revealed tachyzoites attaching to sperm tails, inducing twisting/detachment, and ...
Lisbeth Rojas‐Barón, Leandro Tana‐Hernandez, Mireille H. Nguele Ampama, Raúl Sanchéz, Ulrich Gärtner, Florian M. E. Wagenlehner, Christian Preußer, Elke Pogge von Strandmann, Carlos Hermosilla, Anja Taubert, María E. Francia, Zahady D. Velasquez   +11 more
wiley   +1 more source

Unraveling drug resistance mechanisms in testicular cancer through immune cell phenotypes: a bidirectional Mendelian randomization analysis revealing novel therapeutic targets. [PDF]

Discov Oncol
Xiao L, Wu T.
europepmc   +1 more source

Filarial granuloma of the testicular tunic mimicking a testicular neoplasm: a case report [PDF]

, 2008
Savio George Barreto, J. Rodrigues, Roque G. Wiseman Pinto   +2 more
openalex   +1 more source

Assessment and classification of sex cord‐stromal tumours of the testis: recommendations from the testicular sex cord‐stromal tumour (TESST) group, an Expert Panel of the Genitourinary Pathology Society (GUPS) and International Society of Urological Pathology (ISUP)

Histopathology, EarlyView.
FH immunohistochemistry is recommended in clinically malignant Leydig cell tumours and in primary Leydig cell tumours with aggressive histopathologic features. Aims Testicular sex cord‐stromal tumours (TSCSTs) are relatively rare, accounting for ~5% of all testicular neoplasms.
Andres M Acosta, Maurizio Colecchia, Eva Comperat, Kristine M Cornejo, Anthony J Gill, Sounak Gupta, John C Cheville, Muhammad T Idrees, Chia‐Sui Kao, Fiona Maclean, Andres Matoso, Maria Rosaria Raspollini, Kvetoslava Michalova, Miguel Reyes Mugica, Satish K Tickoo, Toyonori Tsuzuki, Thomas M Ulbright, Sean R Williamson, Stephanie Siegmund, Lynette M Sholl, Pilar Gonzalez‐Peramato, Daniel M Berney   +21 more
wiley   +1 more source

Health risks associated with infertility and non-obstructive azoospermia. [PDF]

Asian J Androl
Huyghe E, Chiu PK.
europepmc   +1 more source

PARP Inhibitors in Genitourinary Cancer: A New Paradigm Beyond Prostate Cancer

International Journal of Urology, EarlyView.
ABSTRACT Alterations in the homologous recombination repair genes, such as BRCA1 and BRCA2, are prevalent in various cancers, presenting a unique opportunity to develop synthetic lethal strategies that target homologous recombination deficiency (HRD).
Yohei Okuda, Taigo Kato, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Koji Hatano, Atsunari Kawashima, Junko Murai, Norio Nonomura   +8 more
wiley   +1 more source