Results 261 to 270 of about 47,128 (346)

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang   +12 more
wiley   +1 more source

Exploring the Incidence of Testicular Neoplasms in the Transgender Population: A Case Series

open access: gold
Elayna M. Shanker   +4 more
openalex   +1 more source

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia   +14 more
wiley   +1 more source

Testicular Tuberculosis Without Epididymitis Simulating Neoplasm

open access: gold, 2008
Alin Chirindel   +3 more
openalex   +1 more source

Exosomal CCT6A Secreted by Cancer‐Associated Fibroblasts Interacts with β‐Catenin to Enhance Chemoresistance and Tumorigenesis in Gastric Cancer

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
Here, it is revealed that CAF‐secreted exosomal CCT6A enhances stemness, chemoresistance, and glycolysis in GC via the β‐catenin/c‐Myc/DDIT4‐TXNIP axis. Furthermore, CCT6P1, a pseudogene of CCT6A, is identified as upregulating CCT6A by competitively binding miR‐922, while c‐Myc transcriptionally activates both CCT6P1 and CCT6A.
Hui Sun   +15 more
wiley   +1 more source

Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 10, October 2025.
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei   +3 more
wiley   +1 more source

Clinical implementation of intensity modulated proton therapy for testicular seminoma. [PDF]

open access: yesActa Oncol
Rønde HS   +8 more
europepmc   +1 more source

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